CAS 1218948-84-5: Valacyclovir hydrochloride hydrate

Description: Valacyclovir hydrochloride hydrate is an antiviral medication primarily used to treat infections caused by certain types of viruses, including herpes simplex virus and varicella-zoster virus. It is the L-valyl ester of acyclovir, which enhances its bioavailability when administered orally. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for formulation in various dosage forms. Its chemical structure includes a valine moiety, which contributes to its pharmacokinetic properties. Valacyclovir is converted to acyclovir in the body, where it exerts its antiviral effects by inhibiting viral DNA synthesis. The hydrochloride salt form enhances stability and solubility. As a hydrate, it contains water molecules in its crystalline structure, which can affect its physical properties and stability. Valacyclovir is generally well-tolerated, but like all medications, it may have side effects and contraindications that should be considered during treatment.

Formula: C₁₃H₂₀N₆O₄.ClH.xH₂O

InChI: InChI=1S/C13H20N6O4.ClH.H2O/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H;1H2/t8-;;/m0../s1

InChI key: InChIKey=KNOVZDRKHSHEQN-JZGIKJSDSA-N

SMILES: Cl.O=C1N=C(N)NC2=C1N=CN2COCCOC(=O)C(N)C(C)C.O

Valacyclovir Hydrochloride

CAS: 1218948-84-5124832-26-4 124832-27-5

• Formula: C₁₃H₂₀N₆O₄·HCl
• Purity: >97.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 360.80

Valacyclovir hydrochloride hydrate

CAS: 1218948-84-5

Valacyclovir HCl hydrate: antiviral prodrug for herpes simplex/zoster/B and ocular herpes treatments.

• Formula: C₁₃H₂₃ClN₆O₅
• Color and Shape: Liquid
• Molecular weight: 378.81