CAS 1219032-18-4

9-Keto Travoprost

CAS: 1219032-18-4

Formula: C₂₆H₃₃F₃O₆

Color and Shape: White To Off-White Solid

Molecular weight: 498.54

Ref: 4Z-T-106018

9-Keto Travoprost

Controlled Product

CAS: 1219032-18-4

Applications 9-Keto Travoprost is an impurity of Travoprost (T715600), a selective FP prostaglandin receptor agonist used to treat glaucoma (1,2).
References Hellberg, M. R., et al.: J. Ocul. Pharmacol. Ther., 17, 421 (2001)

Formula: C₂₆H₃₃F₃O₆

Color and Shape: Neat

Molecular weight: 498.53

Ref: TR-K315195

9-Keto Travoprost

CAS: 1219032-18-4

Formula: C₂₆H₃₃F₃O₆

Molecular weight: 498.54

Ref: ST-EA-CP-T36006

9-keto Fluprostenol isopropyl ester

CAS: 1219032-18-4

9-Keto Fluprostenol Isopropyl Ester, an ester derivative of the FP receptor agonist fluprostenol, undergoes oxidation at carbon 9. This compound serves as a potential prodrug for 9-keto fluprostenol, which may function as an agonist at EP receptors. Additionally, it is considered a possible metabolite of fluprostenol isopropyl ester (travoprost), drawing parallels to the metabolism of latanoprost by 15-hydroxyprostaglandin dehydrogenase observed in monkey cornea. Furthermore, certain F-series prostaglandins, such as 6-keto prostaglandin F1α (PGF1α), undergo conversion to their E-series counterparts in isolated human platelets, highlighting a metabolic pathway of relevance.

Formula: C₂₆H₃₃F₃O₆

Color and Shape: Solid

Molecular weight: 498.5

Ref: TM-T84647