CAS 121961-22-6

Loracarbef monohydrate

Description:

Loracarbef monohydrate is a synthetic antibiotic belonging to the class of beta-lactam antibiotics, specifically a carbapenem. It is primarily used to treat bacterial infections by inhibiting cell wall synthesis in susceptible bacteria. The monohydrate form indicates that the compound contains one molecule of water per molecule of Loracarbef, which can influence its solubility and stability. Loracarbef exhibits a broad spectrum of activity against various gram-positive and gram-negative bacteria, making it effective for respiratory tract infections and other bacterial diseases. Its mechanism of action involves binding to penicillin-binding proteins, disrupting bacterial cell wall formation, and ultimately leading to cell lysis. Loracarbef is generally administered orally and is well-absorbed in the gastrointestinal tract. However, like other antibiotics, it may have side effects, including gastrointestinal disturbances and potential allergic reactions. It is important to use Loracarbef judiciously to minimize the risk of antibiotic resistance.

Formula: C₁₆H₁₆ClN₃O₄·H₂O

InChI: InChI=1S/C16H16ClN3O4.H2O/c17-9-6-7-10-12(15(22)20(10)13(9)16(23)24)19-14(21)11(18)8-4-2-1-3-5-8;/h1-5,10-12H,6-7,18H2,(H,19,21)(H,23,24);1H2/t10-,11-,12+;/m1./s1

InChI key: InChIKey=GPYKKBAAPVOCIW-HSASPSRMSA-N

SMILES: O=C1N2[C@@]([C@@H]1NC([C@H](N)C3=CC=CC=C3)=O)(CCC(Cl)=C2C(O)=O)[H].O

Synonyms:

• (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
• 1-Azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 7-(2R)-aminophenylacetylamino-3-chloro-8-oxo-, monohydrate, (6R,7S)-
• 1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(aminophenylacetyl)amino]-3-chloro-8-oxo-, monohydrate, [6R-[6α,7β(R*)]]-
• 1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-, hydrate (1:1), (6R,7S)-
• 1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-aminophenylacetyl]amino]-3-chloro-8-oxo-, monohydrate, (6R,7S)-
• 7-((Aminophenylacetyl)Amino)-3-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylicaci
• 7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate (1:1)
• Carbacefaclor
• Kt3777
• LY 163892 monohydrate
• Loracarbef monohydrate
• Monohydrate,(6R-(6-Alpha,7-Beta(R*)))-Chloro-8-Oxo

Loracarbef Monohydrate

Controlled Product

CAS: 121961-22-6

Applications Loracarbef (cas# 121961-22-6) is a useful research chemical.

Formula: C₁₆H₁₆ClN₃O₄·H₂O

Color and Shape: Neat

Molecular weight: 367.78

Ref: TR-L469553

Loracarbef monohydrate

CAS: 121961-22-6

Loracarbef is a bactericidal antibiotic that belongs to the group of antimicrobial agents. It is active against a wide range of microorganisms, including aerobic and anaerobic bacteria, Gram-positive cocci, Gram-negative bacilli, spirochetes, and Chlamydia. Loracarbef is used in the treatment of chronic bronchitis in women and streptococcal pharyngitis. It also has been used in combination with radiation therapy for the treatment of patients with cancer. Chemical stability studies have shown that loracarbef monohydrate does not form crystals when mixed with hydrochloric acid or human serum. The compound has been shown to be effective against various strains of bacteria including Staphylococcus aureus and Streptococcus pneumoniae.

Formula: C₁₆H₁₈ClN₃O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 367.78 g/mol

Ref: 3D-WEA96122

Loracarbef (DISCONTINUED)

CAS: 121961-22-6

Antibiotics nesoi

Formula: C₁₆H₁₆ClN₃O₄·H₂O

Color and Shape: Powder

Molecular weight: 349.08293

Ref: 45-1370203