CAS 1219633-99-4

PF-4778574

Description:

PF-4778574, with the CAS number 1219633-99-4, is a chemical compound that has garnered attention in pharmaceutical research, particularly for its potential therapeutic applications. It is classified as a selective inhibitor of certain kinases, which are enzymes that play critical roles in various cellular processes, including cell growth, proliferation, and survival. The compound's structure features specific functional groups that contribute to its biological activity and selectivity. In preclinical studies, PF-4778574 has shown promise in modulating pathways associated with diseases such as cancer and inflammatory disorders. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its efficacy and safety profile in potential therapeutic contexts. As with many investigational compounds, ongoing research is necessary to fully elucidate its mechanism of action, optimal dosing regimens, and potential side effects. Overall, PF-4778574 represents a significant area of interest in the development of targeted therapies in modern medicine.

Formula: C₁₉H₂₂N₂O₃S₂

Synonyms:

• PF-4778574 >=98% (HPLC)
• N-{(3R,4S)-3-[4-(5-Cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl}propane-2-sulfonamide
• N-[(3R,4S)-3-[4-(5-cyanothiophen-2-yl)phenyl]oxan-4-yl]propane-2-sulfonamide
• PF-4778574
• N-[(3R,4S)-3-[4-(5-Cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl]-2-propanesulfonamide
• PF4778574,PF 4778574
• 2-Propanesulfonamide, N-[(3R,4S)-3-[4-(5-cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl]-

PF-4778574

CAS: 1219633-99-4

PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).

Formula: C₁₉H₂₂N₂O₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 390.52

Ref: TM-T16505

PF 4778574

CAS: 1219633-99-4

PF 4778574 is a novel antidepressant drug that belongs to the group of voltage-dependent calcium channel blockers. It has been shown to have neurodevelopmental and neurotrophic properties in vitro, as well as antidepressant effects in animal models. PF 4778574 has also been shown to reduce neuronal cell death induced by glutamate and other excitatory neurotransmitters. The chemical nature of this drug is not yet known, but it may be an l-type calcium channel blocker or a small molecule inhibitor.

Formula: C₁₉H₂₂N₂O₃S₂

Purity: Min. 95%

Molecular weight: 390.52 g/mol

Ref: 3D-UYB63399