CAS 1219739-36-2

Ex229

CAS: 1219739-36-2

Formula: C₂₄H₁₈ClN₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 431.8710

Ref: IN-DA01EN69

EX229

CAS: 1219739-36-2

EX229

Purity: ≥98%

Molecular weight: 431.87g/mol

Ref: 54-BUP04893

EX229

CAS: 1219739-36-2

EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.

Formula: C₂₄H₁₈ClN₃O₃

Purity: 99.20% - 99.36%

Color and Shape: Solid

Molecular weight: 431.87

Ref: TM-TQ0028

AMPK Activator 991

Controlled Product

CAS: 1219739-36-2

Applications AMPK Activator 991 is a small benzimidazole derivative that potently activates AMP-activated protein kinase (AMPK) to increase glucose transport in skeletal muscle, with possible applications in treating a variety of metabolic disorders, such as Type 2 diabetes.
References Lai, Yu-Chiang., et al.: Biochem. J.,460, 363 (2014);

Formula: C₂₄H₁₈ClN₃O₃

Color and Shape: White To Off-White

Molecular weight: 431.87

Ref: TR-A634308

AMPK Activator 991

CAS: 1219739-36-2

AMPK Activator 991 is a small molecule that is structurally related to dinucleotide phosphate. It has been shown to have physiological activities in an animal model, including reducing levels of fatty acids and increasing levels of glucose. AMPK Activator 991 also appears to have beneficial effects on metabolic disorders such as diabetes and obesity, by stimulating the production of cyclic nucleotide phosphodiesterase, which regulates the flow of cyclic nucleotides. This drug also increases camp levels in cells. The α subunit is required for the activity of this compound.

Formula: C₂₄H₁₈ClN₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 431.87 g/mol

Ref: 3D-UYB73936