Valdecoxib-D3 is a deuterated form of valdecoxib, a selective COX-2 inhibitor primarily used for its anti-inflammatory and analgesic properties. As a non-steroidal anti-inflammatory drug (NSAID), it works by inhibiting the cyclooxygenase-2 enzyme, which plays a crucial role in the synthesis of prostaglandins involved in inflammation and pain signaling. The deuteration in Valdecoxib-D3 refers to the substitution of hydrogen atoms with deuterium, a heavier isotope of hydrogen, which can enhance the stability and metabolic profile of the compound. This modification is often utilized in pharmacokinetic studies to trace the compound's behavior in biological systems. Valdecoxib itself has been used in the treatment of conditions such as osteoarthritis and rheumatoid arthritis, although its clinical use has been limited due to safety concerns related to cardiovascular risks. Valdecoxib-D3, while not widely used in clinical settings, serves as a valuable tool in research, particularly in studies investigating the pharmacodynamics and pharmacokinetics of COX-2 inhibitors.

VALDECOXIB-D3

1219794-90-7: Valdecoxib-D3 is a deuterated form of valdecoxib, a selective COX-2 inhibitor primarily used for its anti-inflammatory and analgesic properties. As a non-steroidal anti-inflammatory drug (NSAID), it works by inhibiting the cyclooxygenase-2 enzyme, which plays a crucial role in the synthesis of prostaglandins involved in inflammation and pain signaling. The deuteration in Valdecoxib-D3 refers to the substitution of hydrogen atoms with deuterium, a heavier isotope of hydrogen, which can enhance the stability and metabolic profile of the compound. This modification is often utilized in pharmacokinetic studies to trace the compound's behavior in biological systems. Valdecoxib itself has been used in the treatment of conditions such as osteoarthritis and rheumatoid arthritis, although its clinical use has been limited due to safety concerns related to cardiovascular risks. Valdecoxib-D3, while not widely used in clinical settings, serves as a valuable tool in research, particularly in studies investigating the pharmacodynamics and pharmacokinetics of COX-2 inhibitors.

CAS 1219794-90-7

VALDECOXIB-D3

Valdecoxib-d3

Ref: 4Z-V-091

Valdecoxib-d3 (methyl-d3)

Ref: 3U-D6841

Valdecoxib-d3

Ref: TR-V090003