CAS 1219798-89-6

HYDROCHLOROTHIAZIDE-3,3-D2

Description:

Hydrochlorothiazide-3,3-D2 is a deuterated form of hydrochlorothiazide, a thiazide diuretic commonly used to treat hypertension and edema. The deuteration indicates that the hydrogen atoms in the molecule have been replaced with deuterium, a stable isotope of hydrogen, which can be useful in pharmacokinetic studies and metabolic research. This compound retains the core thiazide structure, characterized by a benzothiadiazine ring fused to a sulfonamide group, which is essential for its diuretic activity. Hydrochlorothiazide works by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased excretion of sodium and water, thereby reducing blood volume and blood pressure. The deuterated version may exhibit altered pharmacokinetic properties, such as changes in metabolism and half-life, which can be advantageous in research settings. As with any pharmaceutical compound, safety and efficacy are paramount, and its use should be guided by clinical evidence and regulatory standards.

Formula: C₇H₆ClD₂N₃O₄S₂

InChI: InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)/i3D2

InChI key: InChIKey=JZUFKLXOESDKRF-SMZGMGDZSA-N

SMILES: O=S1(=O)C=2C(=CC(Cl)=C(S(N)(=O)=O)C2)NC(N1)([2H])[2H]

Synonyms:

• Hydrochlorothiazide D2 Q: What is the storage condition of
• Hydrochlorothiazide D2 Q: What is the CAS Number of
• HYDROCHLOROTHIAZIDE-D2
• Hydrochlorothiazide Impurity 26
• Hydrochlorothiazide D2
• HYDROCHLOROTHIAZIDE-3,3-D2
• [2H2]-Hydrochlorothiazide
• Hydrochlorothiazide D2 Q: What are the applications of
• Hydrochlorothiazide D2Q: What is

Hydrochlorothiazide-3,3-d2

CAS: 1219798-89-6, 58-93-5

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 299.74

Ref: 3U-D6488

Hydrochlorothiazide D2 (3,3-D2)

Controlled Product

CAS: 1219798-89-6

Formula: C₇H₂H₆ClN₃O₄S₂

Color and Shape: Neat

Molecular weight: 299.75

Ref: 04-C14223510

Hydrochlorothiazide Impurity 27

CAS: 1219798-89-6

Formula: C₆H₇ClN₂O₅S₂

Color and Shape: White To Off-White Solid

Molecular weight: 286.70

Ref: 4Z-H-0539

Hydrochlorothiazide-d2

Controlled Product

CAS: 1219798-89-6

Applications Hydrochlorothiazide-d2 is the labeled analogue of Hydrochlorothiazide (H714560), a carbonic anhydrase inhibitor as a diuretic.
References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961); Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981)

Formula: C₇₂H₂H₆ClN₃O₄S₂

Color and Shape: White

Molecular weight: 299.75

Ref: TR-H714561

Hydrochlorothiazide-d2

Controlled Product

CAS: 1219798-89-6

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Formula: C₇H₆ClD₂N₃O₄S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 299.75 g/mol

Ref: 3D-FH183134

Hydrochlorothiazide-d2

CAS: 1219798-89-6

Formula: C₇H₆ClD₂N₃O₄S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 299.7514

Ref: IN-DA009BUP

Hydrochlorothiazide-d2

CAS: 1219798-89-6

Formula: C₉H₈NO₄D₃

Color and Shape: White To Off-White Solid

Molecular weight: 299.75

Ref: 4Z-H-053