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CAS 1219953-64-6

:

1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclopropaneacetic acid

Description:
1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclopropaneacetic acid, commonly referred to as Fmoc-cyclopropaneacetic acid, is a chemical compound characterized by its unique structure that includes a cyclopropane ring and an Fmoc (9-fluorenylmethoxycarbonyl) protecting group. This compound is primarily used in peptide synthesis as a building block due to its ability to protect amino groups during the formation of peptide bonds. The Fmoc group is known for its stability under basic conditions and can be easily removed under mild acidic conditions, making it a popular choice in solid-phase peptide synthesis. The cyclopropaneacetic acid moiety contributes to the compound's rigidity and can influence the conformation of peptides, potentially affecting their biological activity. Additionally, the compound's solubility and reactivity can vary depending on the solvent and conditions used, which is crucial for its application in synthetic chemistry. Overall, Fmoc-cyclopropaneacetic acid is valued for its utility in the synthesis of complex peptides and its role in advancing research in medicinal chemistry and drug development.
Formula:C20H19NO4
InChI:InChI=1S/C20H19NO4/c22-18(23)11-20(9-10-20)21-19(24)25-12-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,21,24)(H,22,23)
InChI key:InChIKey=YWVNZDQHPYFHGS-UHFFFAOYSA-N
SMILES:C(OC(NC1(CC(O)=O)CC1)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3
Synonyms:
  • 2-[1-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)cyclopropyl]acetic acid
  • Cyclopropaneacetic acid, 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-
  • 1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclopropaneacetic acid
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