CAS 122-06-5

stilbamidine

Description:

Stilbamidine, with the CAS number 122-06-5, is an organic compound characterized by its structure as a bis(benzamidine) derivative. It appears as a white to pale yellow crystalline solid and is known for its use in medicinal chemistry, particularly as an antiprotozoal agent. Stilbamidine exhibits a range of biological activities, including potential efficacy against certain parasitic infections. The compound is soluble in organic solvents but has limited solubility in water, which can influence its bioavailability and pharmacokinetics. Its chemical properties include the presence of amine functional groups, which contribute to its reactivity and interaction with biological targets. Stilbamidine's mechanism of action is thought to involve interference with nucleic acid synthesis in pathogens. However, its use may be limited by toxicity and side effects, necessitating careful consideration in therapeutic applications. Overall, stilbamidine serves as an important compound in the study of antiprotozoal therapies and highlights the significance of chemical structure in determining biological activity.

Formula: C₁₆H₁₆N₄

InChI: InChI=1/C16H16N4/c17-15(18)13-7-3-11(4-8-13)1-2-12-5-9-14(10-6-12)16(19)20/h1-10H,(H3,17,18)(H3,19,20)/b2-1+

InChI key: InChIKey=MMURVNDSFNJHAM-UHFFFAOYSA-N

SMILES: C(=N)(N)C1=CC=C(C=CC2=CC=C(C(=N)N)C=C2)C=C1

Synonyms:

• 4,4'-(E)-ethene-1,2-diyldibenzenecarboximidamide
• 4,4'-Ethene-1,2-Diyldibenzenecarboximidamide
• 4,4-Diamidinostilbene
• 4,4′-(1,2-Ethenediyl)bis[benzenecarboximidamide]
• 4,4′-Stilbenedicarboxamidine
• 4,4′-Vinylenedi(benzamidine)
• Ba 2652
• Benzenecarboximidamide, 4,4′-(1,2-ethenediyl)bis-
• Stilbamidin
• Stilbamidine
• 2-(2-phenylethenyl)benzenecarboximidamide

Stilbamidine

CAS: 122-06-5

Stilbamidine

Purity: ≥95%

Molecular weight: 264.33g/mol

Ref: 54-BUP04918

Stilbamidine

CAS: 122-06-5

Stilbamidine (Ba 2652) has antifungal and anticancer activity and can be used to study multiple myeloma and bladder migratory cell carcinoma.

Formula: C₁₆H₁₆N₄

Purity: 97.02% - 97.27%

Color and Shape: Solid

Molecular weight: 264.33

Ref: TM-T13905

Stilbamidine

CAS: 122-06-5

Stilbamidine is a potent inhibitor of cancer cell growth that has been shown to induce apoptosis in Chinese hamster ovary cells. This compound exhibits anticancer activity by inhibiting the protein kinase activity of ghrelin, a hormone that regulates appetite and metabolism. Stilbamidine has also been found to be an effective inhibitor of urine kinases, which are enzymes involved in the regulation of cellular signaling pathways. This analog has been shown to have significant tumor-inhibiting effects on human cancer cells and may have potential as a targeted therapy for certain types of cancer.

Formula: C₁₆H₁₆N₄

Purity: Min. 95%

Molecular weight: 264.32 g/mol

Ref: 3D-AAA12206