CAS 1220-80-0

N-[(4-methylphenyl)sulfonyl]leucine

Description:

N-[(4-methylphenyl)sulfonyl]leucine, with the CAS number 1220-80-0, is an organic compound that belongs to the class of sulfonamides. It features a leucine amino acid backbone, which is an essential branched-chain amino acid, modified by the addition of a sulfonyl group attached to a para-methylphenyl moiety. This structure imparts unique characteristics, including potential biological activity, as sulfonamides are known for their roles in medicinal chemistry, particularly as antibacterial agents. The compound is typically a white to off-white solid, and its solubility can vary depending on the solvent used, often being more soluble in polar solvents. Its melting point and stability can be influenced by environmental conditions such as temperature and pH. N-[(4-methylphenyl)sulfonyl]leucine may exhibit interactions with biological targets, making it of interest in pharmaceutical research. As with many sulfonamides, it is essential to handle this compound with care, considering potential toxicity and environmental impact.

Formula: C₁₃H₁₉NO₄S

InChI: InChI=1/C13H19NO4S/c1-9(2)8-12(13(15)16)14-19(17,18)11-6-4-10(3)5-7-11/h4-7,9,12,14H,8H2,1-3H3,(H,15,16)

SMILES: CC(C)CC(C(=O)O)NS(=O)(=O)c1ccc(C)cc1

Synonyms:

• Leucine, N-[(4-methylphenyl)sulfonyl]-
• N-[(4-Methylphenyl)sulfonyl]leucine

(2S)-4-methyl-2-(4-methylbenzenesulfonamido)pentanoic acid

CAS: 1220-80-0

Formula: C₁₃H₁₉NO₄S

Color and Shape: Solid

Molecular weight: 285.3593

Ref: IN-DA0016KQ

(2S)-4-Methyl-2-(4-methylbenzenesulfonamido)pentanoic acid

CAS: 1220-80-0

(2S)-4-Methyl-2-(4-methylbenzenesulfonamido)pentanoic acid is an inhibitor of aminopeptidases, which are enzymes that catalyze the hydrolysis of peptides and proteins. This drug binds to the active site of the enzyme and inhibits its activity. The inhibition is reversible and competitive. It has been shown that this drug has a high inhibitory effect on aminopeptidases in vitro, but the concentration required for inhibition is higher than the therapeutic level. The interaction between (2S)-4-Methyl-2-(4-methylbenzenesulfonamido)pentanoic acid and chloromethylketone has not been investigated yet.
(2S)-4-Methyl-2-(4-methylbenzenesulfonamido)pentanoic acid is an inhibitor of pancreatic aminopeptidases A, B, C, D,

Formula: C₁₃H₁₉NO₄S

Purity: Min. 95%

Molecular weight: 285.36 g/mol

Ref: 3D-BAA22080