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CAS 122173-74-4

:

Mideplanin

Description:
Mideplanin, with the CAS number 122173-74-4, is a chemical compound that belongs to the class of cyclic peptides. It is primarily recognized for its role as an antibiotic, specifically exhibiting activity against certain bacterial strains. Mideplanin is characterized by its unique cyclic structure, which contributes to its biological activity and stability. The compound has been studied for its potential therapeutic applications, particularly in the treatment of infections caused by resistant bacteria. Its mechanism of action typically involves interference with bacterial cell wall synthesis, leading to cell lysis and death. Mideplanin's pharmacological properties, including its spectrum of activity, toxicity profile, and pharmacokinetics, are essential for understanding its potential use in clinical settings. As with many antibiotics, the development of resistance is a concern, necessitating ongoing research to optimize its use and explore combination therapies. Overall, mideplanin represents a significant compound in the field of medicinal chemistry and antibiotic development.
Formula:C93H109Cl2N11O32
InChI:InChI=1/C93H109Cl2N11O32/c1-38(2)11-8-6-7-9-12-65(115)100-73-79(120)76(117)63(36-108)135-92(73)138-83-60-30-45-31-61(83)132-57-20-16-43(28-52(57)95)82(137-91-72(98-39(3)110)78(119)75(116)62(35-107)134-91)74-90(129)104-71(86(125)97-21-10-22-106(4)5)50-33-47(112)34-59(133-93-81(122)80(121)77(118)64(37-109)136-93)66(50)49-27-42(15-17-54(49)113)68(87(126)105-74)102-89(128)70(45)103-88(127)69-44-25-46(111)32-48(26-44)130-58-29-41(14-18-55(58)114)67(96)85(124)99-53(84(123)101-69)24-40-13-19-56(131-60)51(94)23-40/h13-20,23,25-34,38,53,62-64,67-82,91-93,107-109,111-114,116-122H,6-12,21-22,24,35-37,96H2,1-5H3,(H,97,125)(H,98,110)(H,99,124)(H,100,115)(H,101,123)(H,102,128)(H,103,127)(H,104,129)(H,105,126)
Synonyms:
  • Mideplanin [INN]
  • Mdl 62873
  • A mixture of six substances of which 70% is: 34-((2-acetamido-2-deoxy-beta-D-glucopyranosyl)oxy)-15-amino-22,31-dichloro-56-((2-deoxy-2-(8-methylnonanamido)-beta-D-glucopyranosyl)oxy)-N-(3-(dimethylamino)propyl)-2,3,16,17,18,19,35,36,37,38,48,49,50,50a-tetradecahydro-6,11,40,44-tetrahydroxy-42-(alpha-D-mannopyranosyloxy)-2,16,36,50,51,59-hexaoxo-1H,15H,34H-20,23:30,33-dietheno-3,18,35,48-bis(iminomethano)-4,8,10,14,25,28,43,47-tetrametheno-28H-(1,14,6,22)dioxadiazacyclooctacosino(4,5-m)(10,2,16)benzoxadiazacyclotetracosine-38-carbxamide
  • Ristomycin A aglycone, 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-(2-deoxy-2-((8-methyl-1-oxononyl)amino)-beta-D-glucopyranosyl)-38-(((3-(dimethylamino)propyl)amino)carbonyl)-42-O-alpha-D-mannopyranosyl-
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