CAS 1222102-29-5

Evogliptin

Description:

Evogliptin is a pharmaceutical compound primarily used as an antidiabetic agent, specifically for the management of type 2 diabetes mellitus. It belongs to the class of drugs known as DPP-4 (dipeptidyl peptidase-4) inhibitors, which function by increasing the levels of incretin hormones, thereby enhancing insulin secretion and reducing glucagon levels in the bloodstream. This mechanism helps to lower blood glucose levels after meals. Evogliptin is characterized by its selective inhibition of the DPP-4 enzyme, which contributes to its efficacy and safety profile. The compound is typically administered orally and is often used in combination with other antidiabetic medications to achieve better glycemic control. Its chemical structure includes a specific arrangement of atoms that contributes to its biological activity and pharmacokinetic properties. As with any medication, potential side effects may occur, and it is essential for patients to consult healthcare professionals for personalized advice and monitoring during treatment.

Formula: C₁₉H₂₆F₃N₃O₃

InChI: InChI=1S/C19H26F3N3O3/c1-19(2,3)28-10-16-18(27)24-4-5-25(16)17(26)8-12(23)6-11-7-14(21)15(22)9-13(11)20/h7,9,12,16H,4-6,8,10,23H2,1-3H3,(H,24,27)/t12-,16-/m1/s1

InChI key: InChIKey=LCDDAGSJHKEABN-MLGOLLRUSA-N

SMILES: C(C[C@@H](CC1=C(F)C=C(F)C(F)=C1)N)(=O)N2[C@H](COC(C)(C)C)C(=O)NCC2

Synonyms:

• 2-Piperazinone, 4-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-3-[(1,1-dimethylethoxy)methyl]-, (3R)-
• DA 1229
• (3R)-4-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-3-[(1,1-dimethylethoxy)methyl]-2-piperazinone
• Evogliptin

ent-Evogliptin L-Tartrate Salt

Controlled Product

CAS: 1222102-29-5

Formula: C₁₉H₂₆F₃N₃O₃•C₄H₆O₆

Color and Shape: Neat

Molecular weight: 401.42 + 150.09

Ref: TR-E945900

(3'S)-Evogliptin L-tartrate Salt

Controlled Product

CAS: 1222102-29-5

Formula: C₁₉H₂₆F₃N₃O₃•C₄H₆O₆

Color and Shape: Neat

Molecular weight: 401.42 + 150.09

Ref: TR-E945905

(4'S)-Evogliptin L-Tartrate Salt

Controlled Product

CAS: 1222102-29-5

Formula: C₁₉H₂₆F₃N₃O₃•C₄H₆O₆

Color and Shape: Neat

Molecular weight: 401.42 + 150.09

Ref: TR-E945910

Evogliptin

CAS: 1222102-29-5

Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.

Formula: C₁₉H₂₆F₃N₃O₃

Color and Shape: Solid

Molecular weight: 401.42

Ref: TM-T61949