CAS 122292-85-7

(-)-Trichostatin A

CAS: 122292-85-7

Formula: C₁₇H₂₂N₂O₃

Purity: >98.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 302.37

Ref: 3B-T3633

2,4-Heptadienamide,7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, [S-(E,E)]-

CAS: 122292-85-7

Formula: C₁₇H₂₂N₂O₃

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 302.3682

Ref: IN-DA00IML8

(-)-Trichostatin A

CAS: 122292-85-7

(-)-Trichostatin A is a histone deacetylase inhibitor that has been shown to inhibit the growth of cancer cells. It is able to bind to the nucleosome, which is an aggregate of eight histone proteins and two copies of DNA, and inhibits the binding or transcriptional activation of genes. (-)-Trichostatin A also inhibits the methylation of histones by inhibiting methyltransferases. This inhibition leads to increased expression of tumor suppressor genes and decreased cell proliferation in vitro. (-)-Trichostatin A has also been shown to inhibit collagen gel contraction and increase collagen gel elasticity in vitro. - (-)-Trichostatin A may be a potential therapeutic agent for prostate cancer; however, this has not yet been confirmed in vivo studies.

Formula: C₁₇H₂₂N₂O₃

Purity: Min. 95%

Molecular weight: 302.37 g/mol

Ref: 3D-XEA29285

Trichostatin A S-isomer

CAS: 122292-85-7

Trichostatin A S-isomer, a HDAC 1, 3, 4, 6, 10 inhibitor with IC50 ~20 nM, has wide-ranging epigenetic effects.

Formula: C₁₇H₂₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 302.37

Ref: TM-T29007