CAS 1223001-51-1

9-(6-AMino-pyridin-3-yl)-1-(3-trifluoroMethyl-phenyl)-1H-benzo[h][1,6]naphthyridin-2-one

Description:

The chemical substance known as 9-(6-amino-pyridin-3-yl)-1-(3-trifluoromethyl-phenyl)-1H-benzo[h][1,6]naphthyridin-2-one, with the CAS number 1223001-51-1, is a complex organic compound characterized by its unique structural features, including a benzo[h][1,6]naphthyridine core. This compound contains multiple functional groups, such as an amino group and a trifluoromethyl group, which can significantly influence its chemical reactivity and biological activity. The presence of the amino group may enhance its solubility in polar solvents and facilitate interactions with biological targets, while the trifluoromethyl group can impart unique electronic properties and lipophilicity. Such characteristics make this compound of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. Its molecular structure suggests potential applications in areas such as cancer research or as a therapeutic agent, although further studies would be necessary to elucidate its specific biological effects and mechanisms of action.

Synonyms:

• Torin 2

Benzo[h]-1,6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-

CAS: 1223001-51-1

Formula: C₂₄H₁₅F₃N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 432.3973

Ref: IN-DA001729

Torin2

CAS: 1223001-51-1

Torin2

Purity: 97%

Molecular weight: 432.405g/mol

Ref: 54-PC105435

Torin 2

CAS: 1223001-51-1

Torin 2

Purity: ≥98%

Molecular weight: 432.4g/mol

Ref: 54-BUP09964

Torin 2

CAS: 1223001-51-1

Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.

Formula: C₂₄H₁₅F₃N₄O

Purity: 98.31% - 99.32%

Color and Shape: Solid

Molecular weight: 432.4

Ref: TM-T6100

Torin 2

Controlled Product

CAS: 1223001-51-1

Applications Torin 2 is a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer.
References Liu, Q.S., et al.: J. Med. Chem., 54, 1473 (2011);

Formula: C₂₄H₁₅F₃N₄O

Color and Shape: Neat

Molecular weight: 432.4

Ref: TR-T548710

Torin 2

CAS: 1223001-51-1

mTOR inhibitor

Formula: C₂₄H₁₅F₃N₄O

Purity: Min. 95%

Molecular weight: 432.4 g/mol

Ref: 3D-FT102223