CAS 1223403-58-4: (3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-1-pyrrolidinecarboxamide

Description:The chemical substance with the name "(3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-1-pyrrolidinecarboxamide" and CAS number "1223403-58-4" is characterized by its complex molecular structure, which includes multiple functional groups and stereocenters. This compound features a pyrrolidine backbone, which contributes to its potential biological activity. The presence of a difluorophenyl group suggests that it may exhibit unique electronic properties, potentially influencing its interaction with biological targets. The pyrazolo[1,5-a]pyrimidine moiety is indicative of its possible role in medicinal chemistry, particularly in the development of pharmaceuticals. The hydroxyl and carboxamide functional groups may enhance solubility and bioavailability, making it a candidate for therapeutic applications. Overall, this compound's intricate structure and functional diversity suggest it may have significant implications in drug discovery and development, particularly in areas related to neurological or oncological research. Further studies would be necessary to elucidate its specific biological activities and mechanisms of action.

Formula:C₂₁H₂₂F₂N₆O₂

InChI:InChI=1S/C21H22F2N6O2/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18+/m0/s1

InChI key:InChIKey=NYNZQNWKBKUAII-KBXCAEBGSA-N

SMILES:O=C(NC=1C=NN2C=CC(=NC12)N3CCCC3C4=CC(F)=CC=C4F)N5CCC(O)C5

Synonyms:
(3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-1-pyrrolidinecarboxamide
(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
1-Pyrrolidinecarboxamide, N-[5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-, (3S)-
Arry-470
Larotrectinib
LOXO 101

Found 8 products.

Product data	Purity	Price range	Estimated delivery
1-Pyrrolidinecarboxamide, N-[5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-, (3S)- REF: IN-DA00174HCAS: 1223403-58-4	98%	To inquire	Tue 15 Apr 25
Larotrectinib REF: 54-BUP08919CAS: 1223403-58-4	99.15%	257.00 €~1,173.00 €	Mon 14 Apr 25
Larotrectinib REF: 4Z-L-160001CAS: 1223403-58-4	- - -	To inquire	Mon 14 Apr 25
LarotrectinibFor REF: 54-PC108871CAS: 1223403-58-4	99%	183.00 €~1,784.00 €	Mon 14 Apr 25
Larotrectinib REF: TM-T5995CAS: 1223403-58-4	100% - 99.15%	39.00 €~867.00 €	Tue 22 Apr 25
Larotrectinib-d7 REF: 4Z-L-160003CAS: 1223403-58-4	- - -	To inquire	Tue 22 Apr 25
Larotrectinib REF: 10-F861810CAS: 1223403-58-4	97%	To inquire	Wed 23 Apr 25
Larotrectinib REF: 3D-FD145150CAS: 1223403-58-4	Min. 98 Area-%	143.00 €~881.00 €	Thu 24 Apr 25