Description:FMOC-GLU-OBZL, with the CAS number 122350-52-1, is a chemical compound commonly used in peptide synthesis and research. It is a derivative of glutamic acid, where the FMOC (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, facilitating the selective modification of the carboxylic acid group. The OBZL (benzyl ester) moiety protects the carboxylic acid, enhancing the stability and solubility of the compound during synthesis. This compound is typically utilized in solid-phase peptide synthesis, allowing for the sequential addition of amino acids to form peptides. Its characteristics include good solubility in organic solvents, stability under standard laboratory conditions, and compatibility with various coupling reagents. The protective groups can be removed under specific conditions, enabling the release of the functional amino acid for further reactions. Overall, FMOC-GLU-OBZL is a valuable intermediate in the synthesis of peptides and other bioactive molecules in medicinal chemistry and biochemistry.
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