CAS 122397-46-0

alldimycin A

Description:

Alldimycin A, with the CAS number 122397-46-0, is a natural product belonging to the class of compounds known as antibiotics. It is derived from the fermentation of specific strains of Streptomyces bacteria. This compound exhibits a complex molecular structure characterized by multiple rings and functional groups, which contribute to its biological activity. Alldimycin A is known for its potent antibacterial properties, particularly against Gram-positive bacteria, making it a subject of interest in pharmaceutical research. Its mechanism of action typically involves interference with bacterial protein synthesis, leading to cell growth inhibition. Additionally, the compound may exhibit cytotoxic effects, which can be leveraged in cancer research. The stability, solubility, and bioavailability of alldimycin A are important factors that influence its therapeutic potential. As with many antibiotics, the development of resistance is a concern, prompting ongoing studies to optimize its efficacy and explore its use in combination therapies. Overall, alldimycin A represents a valuable compound in the search for effective antimicrobial agents.

Formula: C₂₈H₃₃NO₁₀

InChI: InChI=1/C28H33NO10/c1-5-28(37)10-17(39-18-9-14(29(3)4)23(32)11(2)38-18)12-8-13-19(25(34)20(12)27(28)36)26(35)22-16(31)7-6-15(30)21(22)24(13)33/h6-8,11,14,17-18,23,27,30-32,34,36-37H,5,9-10H2,1-4H3

Synonyms:

• 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,4,6,7,8-pentahydroxy-10-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-
• 3-ethyl-3,4,5,7,10-pentahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)hexopyranoside
• Alldimycin A
• (7R)-8-Ethyl-7,8,9,10-tetrahydro-1,4,6,7β,8α-pentahydroxy-10α-[[3-(dimethylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]5,12-naphthacenedione
• 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,4,6,7,8-pentahydroxy-10-[[2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-, (7R,8R,10S)- (9CI)

Alldimycin A

CAS: 122397-46-0

Alldimycin A is an anthracycline compound that inhibits the synthesis of RNA and DNA. It effectively hampers the growth of mouse leukemia L1210 cells and reduces DNA and RNA synthesis, with IC50 values of 0.05 μg/mL, 0.92 μg/mL, and 0.47 μg/mL, respectively.

Formula: C₂₈H₃₃NO₁₀

Color and Shape: Solid

Molecular weight: 543.562

Ref: TM-TN9077