CAS 12244-57-4

Gold sodium thiomalate

Description:

Gold sodium thiomalate is a chemical compound that serves primarily as a therapeutic agent in the treatment of rheumatoid arthritis. It is a gold-containing complex where gold is coordinated with thiomalate, a derivative of thiolactic acid. This compound is characterized by its ability to modulate immune responses and reduce inflammation, which is beneficial in managing autoimmune conditions. Gold sodium thiomalate is typically administered via intramuscular injection and is known for its slow-release properties, allowing for prolonged therapeutic effects. The compound is soluble in water, which facilitates its use in medical formulations. Its mechanism of action involves the inhibition of macrophage activity and the modulation of cytokine production, contributing to its anti-inflammatory effects. While it can be effective, potential side effects may include skin reactions, gastrointestinal disturbances, and hematological changes, necessitating careful monitoring during treatment. Overall, gold sodium thiomalate represents a unique intersection of inorganic chemistry and pharmacology, highlighting the therapeutic potential of metal-based compounds in medicine.

Formula: C₄H₆O₄S·Au·xNa

InChI: InChI=1S/C4H6O4S.Au.Na/c5-3(6)1-2(9)4(7)8;;/h2,9H,1H2,(H,5,6)(H,7,8);;

InChI key: InChIKey=AATVVBHCZDQBFG-UHFFFAOYSA-N

SMILES: C(CC(O)=O)(C(O)=O)S.[Au].[Na]

Synonyms:

• Aurolate
• Aurothiomalate sodium
• Butanedioic acid, 2-mercapto-, gold(1+) sodium salt (1:1:?)
• Butanedioic acid, mercapto-, monogold(1+) sodium salt
• Chrysothios
• Disodium 2-(Auriothio)Succinate
• Gold sodium Thiomalate
• Gold(1+) Sodium 2-Sulfidobutanedioate (1:2:1)
• Gold(1+) Sodium 2-Sulfidobutanedioate Hydrate (1:2:1:1)
• Kidon
• Miocrisina
• Myochrysin
• Myochrysine
• Myocrisin
• Shiosol
• Sodium Aurothiomalate Hydrate
• Sodium aurithiomalate
• Tauredon

Sodium aurothiomalate(I), 99.9% (metals basis)

CAS: 12244-57-4

Sodium aurothiomalate(I) is useful for high mobility group box chromosomal protein 1 western blotting. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aes

Formula: C₄H₃AuNa₂O₄S

Purity: 99.9%

Molecular weight: 390.08

Ref: 02-039740

Sodium aurothiomalate

CAS: 12244-57-4

Formula: C₄H₆AuNaO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 370.1094

Ref: IN-DA001790

Gold Sodium Thiomalate

CAS: 12244-57-4

Gold Sodium Thiomalate

Purity: 99.9%

Molecular weight: 390.08g/mol

Ref: 54-IN11715

Aurothiomalate sodium

CAS: 12244-57-4

Aurothiomalate sodium

Purity: ≥98%

Ref: 54-BUP06470