CAS 122483-84-5

Angiotensin I/II (3-7)

Description:

Angiotensin I and II are peptides that play crucial roles in the regulation of blood pressure and fluid balance in the body. Angiotensin I is a precursor that is converted into Angiotensin II, a potent vasoconstrictor, by the action of the enzyme angiotensin-converting enzyme (ACE). The specific fragment "Angiotensin II (3-7)" refers to a bioactive segment of the Angiotensin II peptide, which is involved in various physiological processes, including the modulation of blood pressure and electrolyte balance. The CAS number 122483-84-5 identifies a specific chemical substance related to this peptide. Characteristics of Angiotensin II (3-7) include its peptide structure, which consists of a sequence of amino acids, and its ability to interact with specific receptors in the renin-angiotensin system. This interaction can influence cardiovascular function and is a target for certain antihypertensive medications. Overall, Angiotensin II (3-7) is significant in both physiological and pharmacological contexts, particularly in the management of hypertension and heart failure.

Formula: C₃₁H₄₅N₇O₇

InChI: InChI=1/C31H45N7O7/c1-5-18(4)26(37-27(40)22(35-28(41)25(32)17(2)3)13-19-8-10-21(39)11-9-19)29(42)36-23(14-20-15-33-16-34-20)30(43)38-12-6-7-24(38)31(44)45/h8-11,15-18,22-26,39H,5-7,12-14,32H2,1-4H3,(H,33,34)(H,35,41)(H,36,42)(H,37,40)(H,44,45)/t18-,22-,23-,24-,25-,26-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)O)N=C([C@H](Cc1ccc(cc1)O)N=C([C@H](C(C)C)N)O)O

Synonyms:

• H-Val-Tyr-Ile-His-Pro-OH
• L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-proline

Angiotensin I/II (3-7)

CAS: 122483-84-5

Bachem ID: 4014701.

Formula: C₃₁H₄₅N₇O₇

Purity: 99.1%

Color and Shape: White Powder

Molecular weight: 627.74

Ref: 01-4014701

2-6-Angiotensin III,4-L-isoleucine-

CAS: 122483-84-5

Formula: C₃₁H₄₅N₇O₇

Purity: 99%

Color and Shape: Solid

Molecular weight: 627.7317

Ref: IN-DA0080MV

Angiotensin I/II (3-7)

CAS: 122483-84-5

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₃₁H₄₅N₇O₇

Molecular weight: 627.75 g/mol

Ref: 3D-PP50190

Angiotensin I/II (3-7)

CAS: 122483-84-5

Angiotensin I/II (3-7) H-Val-Tyr-Ile-His-Pro-OH is an antagonist of the angiotensin II receptor. It has been shown to be a cognitive enhancer by statistically improving treatments for behavioural problems in rats and mice. Angiotensin I/II (3-7) H-Val-Tyr-Ile-His-Pro-OH has also been shown to inhibit nicotinic acetylcholine receptors, which are involved in mediating the effects of neurotransmitters on muscle cells. This agent also inhibits angiotensin II receptors, leading to vasodilation and reduced blood pressure. The mechanism of action is not yet clear but may involve inhibition of protein kinase C. In preclinical studies, it has been shown that this drug facilitates behavioural effects such as memory retention and motor performance in rats when given before treatment with peptides such as substance P or calcitonin gene related pept

Formula: C₃₁H₄₅N₇O₇

Purity: Min. 95%

Molecular weight: 627.73 g/mol

Ref: 3D-FA109995