CAS 1225-60-1

Isothipendyl hydrochloride

Description:

Isothipendyl hydrochloride is a chemical compound primarily recognized for its antihistaminic properties, making it useful in the treatment of allergic conditions. It belongs to the class of drugs known as antihistamines, which function by blocking the action of histamine at H1 receptors, thereby alleviating symptoms such as itching, sneezing, and runny nose. The compound is typically presented as a white to off-white crystalline powder and is soluble in water, which facilitates its formulation in various pharmaceutical preparations. Isothipendyl hydrochloride has a relatively low toxicity profile, but like many antihistamines, it may cause side effects such as drowsiness, dry mouth, or dizziness. Its pharmacological effects are attributed to its ability to cross the blood-brain barrier, although it is generally less sedating than first-generation antihistamines. The compound is often used in combination with other medications to enhance therapeutic efficacy in managing allergic reactions and respiratory conditions. As with any medication, it is important to use isothipendyl hydrochloride under medical supervision to ensure safety and effectiveness.

Formula: C₁₆H₁₉N₃S·ClH

InChI: InChI=1S/C16H19N3S.ClH/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-16(15)19;/h4-10,12H,11H2,1-3H3;1H

InChI key: InChIKey=RQHCFTORMXCNGP-UHFFFAOYSA-N

SMILES: C(C(N(C)C)C)N1C=2C(SC=3C1=NC=CC3)=CC=CC2.Cl

Synonyms:

• 10-(2-Dimethylamino-2-methylethyl)-10H-pyrido(3,2-b)(1,4)benzothiazine hydrochloride
• 10-(2-Dimethylaminopropyl)-(1)-4-azaphenthiazin hydrochlorid
• 10-(2-Dimethylaminopropyl)-(1)-4-azaphenthiazin hydrochlorid [German]
• 10-(2-Dimethylaminopropyl)-1-azaphenothiazine hydrochloride
• 10-(2-Dimethylaminopropyl)-10H-pyrido(3,2-b)(1,4)benzothiazine hydrochloride
• 10-(2-Dimethylaminopropyl)-9-thia-1,10-diazaanthracene hydrochloride
• 10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(2-(dimethylamino)propyl)-, monohydrochloride
• 10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(2-(dimethylamino)propyl)-, monohydrochloride (8CI)
• 10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(2-dimethylamino-2-methylethyl)-, hydrochloride
• 10H-Pyrido(3,2-b)(1,4)benzothiazine-10-ethanamine, N,N,2-trimethyl-, monohydrochloride (9CI)
• 10H-Pyrido[3,2-b][1,4]benzothiazine-10-ethanamine, N,N,α-trimethyl-, hydrochloride (1:1)
• 10H-Pyrido[3,2-b][1,4]benzothiazine-10-ethanamine, N,N,α-trimethyl-, monohydrochloride
• Adantol
• Adanton hydrochloride
• Andantol
• Andanton
• Dimethylamino-isopropyl-thiophenyl-pyridylamin hydrochlorid
• Dimethylamino-isopropyl-thiophenyl-pyridylamin hydrochlorid [German]
• Isothipendyl HCl
• Isothipendyl hydrochloride [JAN]
• Isothipendyl monohydrochloride
• N,N-dimethyl-1-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propan-2-amine hydrochloride (1:1)
• N-Dimethylaminoisopropylthiophenylpyridylamine hydrochloride
• Nilergex
• Nilergex hydrochloride
• Nsc 169186
• Theruhistin
• Theruhistin hydrochloride
• Udantol hydrochloride
• Unii-953Ap1Lbv8
• Isothipendyl hydrochloride

Isothipendyl Hydrochloride

CAS: 1225-60-1

Color and Shape: Neat

Ref: 61-FOR1009.00

Isothipendyl HCl

CAS: 1225-60-1

Formula: C₁₆H₁₉N₃S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 285.41 36.46

Ref: 4Z-I-052002

Isothipendyl Hydrochloride

Controlled Product

CAS: 1225-60-1

Formula: C₁₆H₁₉N₃S·ClH

Color and Shape: Neat

Molecular weight: 321.87

Ref: 86-MM1009.00

Isothipendyl hydrochloride

CAS: 1225-60-1

Isothipendyl hydrochloride is a crystalline cellulose derivative that is used as an excipient in pharmaceutical preparations. It has been shown to inhibit the growth of animal cells and bacteria, including Gram-positive and Gram-negative bacteria, with optimum concentrations ranging from 3 to 30%. Isothipendyl hydrochloride has also been shown to have anti-inflammatory properties against inflammatory diseases, such as allergic rhinitis and asthma. Isothipendyl hydrochloride may also be used for the treatment of autoimmune diseases, such as psoriasis or rheumatoid arthritis. Isothipendyl hydrochloride has also been shown to have anti-cancer activity, inhibiting skin cancer cell growth. This may be due to its effects on receptor activity by inhibiting certain cellular functions necessary for tumor cell proliferation. Isothipendyl hydrochloride can be prepared by reacting thiourea with 2-aminoethanol followed by hydro

Formula: C₁₆H₂₀ClN₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 321.87 g/mol

Ref: 3D-FI30144

a-Isothipendyl Hydrochloride

Controlled Product

CAS: 1225-60-1

Stability Hygrscopic
Applications Antihistaminic.
References Milsmann, E., et al.: Dermatologica, 170, 230 (1985), Turcant, A., et al.: Clin. Chem., 37, 1210 (1991),

Formula: C₁₆H₁₉N₃S·ClH

Color and Shape: Neat

Molecular weight: 321.87

Ref: TR-I902750

Isothipendyl Hydrochloride

CAS: 1225-60-1

Formula: C₁₆H₁₉N₃SHCl

Molecular weight: 285.41 : 36.46

Ref: ST-EA-CP-I78001

Isothipendyl hydrochloride

CAS: 1225-60-1

Isothipendyl hydrochloride is a 1st generation H1 antagonist.

Formula: C₁₆H₂₀ClN₃S

Color and Shape: Solid

Molecular weight: 321.87

Ref: TM-T24181