CAS 1225-65-6

Prothipendyl hydrochloride

Description:

Prothipendyl hydrochloride is a chemical compound primarily recognized for its use as an antihistamine and antiallergic agent. It belongs to the class of piperidine derivatives and is characterized by its ability to block histamine H1 receptors, thereby alleviating allergic symptoms. The compound appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in pharmaceutical formulations. Prothipendyl hydrochloride is often utilized in the treatment of allergic conditions such as rhinitis and urticaria. Its pharmacological profile includes sedative properties, which can lead to drowsiness, a common side effect associated with many first-generation antihistamines. The compound's efficacy and safety profile make it a valuable option in managing allergic reactions, although it is essential to consider potential interactions with other medications and individual patient responses. As with any pharmaceutical agent, proper dosage and adherence to medical guidelines are crucial for achieving the desired therapeutic outcomes while minimizing adverse effects.

Formula: C₁₆H₁₉N₃S·ClH

InChI: InChI=1S/C16H19N3S.ClH/c1-18(2)11-6-12-19-13-7-3-4-8-14(13)20-15-9-5-10-17-16(15)19;/h3-5,7-10H,6,11-12H2,1-2H3;1H

InChI key: InChIKey=CQJSAKJMCVSEGU-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(SC=3C1=NC=CC3)=CC=CC2.Cl

Synonyms:

• ((4-Dimethylaminopropylpyrido (3,2b) benzothiazine)) hydrochloride
• 10-(3-Dimethylaminopropyl)-1-azaphenothiazine hydrochloride
• 10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(3-(dimethylamino)propyl)-, monohydrochloride
• 10H-Pyrido[3,2-b][1,4]benzothiazine-10-propanamine, N,N-dimethyl-, hydrochloride (1:1)
• 10H-Pyrido[3,2-b][1,4]benzothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride
• Ay-56031
• Azacon
• D 206
• Dominal forte
• Dominal hydrochloride
• Iso-Thiopental
• N,N-Dimethyl-10H-pyrido(3,2-b)(1,4)benzothiazine-10-propanamine, monohydrochloride
• Prothipendyl HCl
• Prothipendyl hydrochloride
• Prothipendyl monohydrochloride
• Tolnate
• Unii-7610629Rvh

Prothipendyl Hydrochloride

CAS: 1225-65-6

Applications A Phenothiazine (P318040) analog. Antipsychotic.
References Sartorelli, A.C., et al.: Experientia, 21, 457 ( 1965),

Formula: C₁₆H₁₉N₃S·ClH

Color and Shape: Neat

Molecular weight: 321.87

Ref: TR-P838850

Prothipendyl hydrochloride

CAS: 1225-65-6

Prothipendyl hydrochloride serves as an orally active compound for researching mental symptoms in the elderly, such as anxiety [1].

Formula: C₁₆H₂₀ClN₃S

Color and Shape: Solid

Molecular weight: 321.87

Ref: TM-T81368

Prothipendyl hydrochloride

Controlled Product

CAS: 1225-65-6

Prothipendyl hydrochloride is a low-potency, non-selective 5-HT receptor antagonist. It is used in the treatment of depression and anxiety disorders. Prothipendyl hydrochloride has been shown to be effective in treating Parkinson's disease and other movement disorders by blocking the action of dopamine on 5-HT receptors. Prothipendyl hydrochloride also has been shown to have cardiac effects. It binds to cardiac tissue with high affinity, which may be due to its ability to bind nitrogen atoms. Prothipendyl hydrochloride is not active against human liver cells, which may be due to its specificity for cb2 receptors that are found only in the central nervous system.

Formula: C₁₆H₂₀ClN₃S

Purity: Min. 95%

Molecular weight: 321.87 g/mol

Ref: 3D-FP27245