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CAS 122520-86-9

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Tyrphostin AG 213

Description:
Tyrphostin AG 213 is a synthetic compound that functions primarily as a selective inhibitor of receptor tyrosine kinases, particularly the epidermal growth factor receptor (EGFR). This compound is part of a broader class of tyrphostins, which are known for their ability to interfere with signal transduction pathways involved in cell growth and proliferation. Tyrphostin AG 213 has been studied for its potential therapeutic applications in cancer treatment, as it can inhibit tumor cell growth by blocking the signaling pathways that promote cell division. The compound is characterized by its specific chemical structure, which includes functional groups that facilitate its interaction with target proteins. Additionally, it is typically used in research settings to explore the mechanisms of cancer biology and the role of tyrosine kinases in various cellular processes. As with many chemical substances, safety and handling precautions are essential when working with Tyrphostin AG 213, given its biological activity and potential effects on cellular systems.
Formula:C10H8N2O2S
InChI:InChI=1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+
InChI key:InChIKey=ZGHQGWOETPXKLY-XVNBXDOJSA-N
SMILES:C(=C(/C(N)=S)\C#N)\C1=CC(O)=C(O)C=C1
Synonyms:
  • (2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenethioamide
  • (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide
  • 2-Propenethioamide, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)-
  • 2-Propenethioamide, 2-cyano-3-(3,4-dihydroxyphenyl)-, (E)-
  • 3-Amino-2-[(3-Hydroxy-4-Oxocyclohexa-2,5-Dien-1-Ylidene)Methyl]-3-Sulfanylprop-2-Enenitrile
  • Alpha-Cyano-(3,4-Dihydroxy)Thiocinnamide
  • Alpha-Cyano-3,4-Dihydroxythiocinnamamide
  • Rg-50864
  • Tyrphostin 47
  • Tyrphostin A47
  • See more synonyms
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