CAS 122576-59-4

26-deoxymonensin A

Description:

26-Deoxymonensin A is a chemical compound belonging to the class of polyether antibiotics, which are known for their ability to form complexes with cations, particularly sodium and potassium ions. This compound is derived from the fermentation of certain strains of the bacterium *Streptomyces cinnamonensis*. It exhibits a unique structure characterized by a macrocyclic lactone ring, which contributes to its biological activity. 26-Deoxymonensin A is primarily recognized for its ionophoric properties, allowing it to transport ions across biological membranes, thereby influencing cellular processes. Its applications are notable in veterinary medicine, particularly as a growth promoter and coccidiostat in livestock. Additionally, it has been studied for its potential effects on various biological systems, including its antimicrobial and antiparasitic activities. The compound's stability, solubility, and interaction with other substances are essential factors that influence its efficacy and safety in practical applications. As with many antibiotics, the development of resistance and regulatory considerations are important aspects of its use in agriculture and medicine.

Formula: C₃₆H₆₂O₁₀

InChI: InChI=1/C36H62O10/c1-11-35(31-20(3)17-26(42-31)28-19(2)16-21(4)34(9,40)44-28)13-12-27(43-35)33(8)14-15-36(46-33)18-25(37)22(5)30(45-36)23(6)29(41-10)24(7)32(38)39/h19-31,37,40H,11-18H2,1-10H3,(H,38,39)

SMILES: CCC1(CCC(C2(C)CCC3(CC(C(C)C(C(C)C(C(C)C(=O)O)OC)O3)O)O2)O1)C1C(C)CC(C2C(C)CC(C)C(C)(O)O2)O1

Synonyms:

• Monensin, 26-deoxy-
• 4-{2-[2-ethyl-5'-(6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)-3'-methyloctahydro-2,2'-bifuran-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl}-3-methoxy-2-methylpentanoic acid
• 26-Deoxymonensin A
• 4-[2-[5-ethyl-5-[5-(6-hydroxy-3,5,6-trimethyloxan-2-yl)-3-methyloxolan-2-yl]oxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoic acid

26-Deoxymonensin A Sodium Salt

CAS: 122576-59-4

Applications 26-Deoxymonensin A Sodium Salt is a metabolite of Monensin (M515600, Na salt); a polyether antibiotic and coccidiostat.
References Pospisil, S., et al.: Appl. Environ. Microb., 60, 1561 (1994); Ashworth, D.M., et al.: J. Antibiot., 42, 1088 (1989);

Formula: C₃₆H₆₁O₁₀·Na

Color and Shape: Neat

Molecular weight: 676.85

Ref: TR-D243000