CAS 122647-31-8: Ibutilide

Description: Ibutilide is a class III antiarrhythmic agent primarily used in the management of atrial fibrillation and atrial flutter. It functions by prolonging the cardiac action potential and refractory period, which helps restore normal heart rhythm. Chemically, ibutilide is characterized by its structure, which includes a butyl side chain and an aromatic ring, contributing to its pharmacological properties. It is typically administered intravenously and is known for its rapid onset of action. The substance exhibits a moderate bioavailability and is metabolized primarily in the liver, with renal excretion of its metabolites. Common side effects may include QT interval prolongation, which can lead to potentially life-threatening arrhythmias, necessitating careful monitoring during administration. Due to its specific mechanism of action and potential side effects, ibutilide is generally reserved for use in a hospital setting under close supervision. Overall, ibutilide represents a critical option in the pharmacological management of certain cardiac arrhythmias, highlighting the importance of understanding its characteristics and effects in clinical practice.

Formula: C₂₀H₃₆N₂O₃S

InChI: InChI=1S/C20H36N2O3S/c1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25/h12-15,20-21,23H,4-11,16-17H2,1-3H3

InChI key: InChIKey=ALOBUEHUHMBRLE-UHFFFAOYSA-N

SMILES: O=S(=O)(NC1=CC=C(C=C1)C(O)CCCN(CC)CCCCCCC)C

Synonyms:

• Ibutilida
• Ibutilida [INN-Spanish]
• Ibutilide [INN:BAN]
• Ibutilidum
• Ibutilidum [INN-Latin]
• Methanesulfonamide, N-[4-[4-(ethylheptylamino)-1-hydroxybutyl]phenyl]-
• N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamide (2E)-but-2-enedioate (salt)
• N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamide
• Unii-2436Vx1U9B
• Ibutilide

Ibutilide

CAS: 122647-31-8

• Formula: C₂₀H₃₆N₂O₃S
• Molecular weight: 384.58

Ibutilide Hemifumarate

CAS: 122647-31-8122647-32-9

• Formula: C₂₀H₃₆N₂O₃SC₄H₄O₄
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 442.62

Ibutilide

CAS: 122647-31-8

Ibutilide (U70226E) is an antiarrhythmic that prolongs action potential by blocking I Kr in AT-1 …

• Formula: C₂₀H₃₆N₂O₃S
• Color and Shape: Liquid
• Molecular weight: 384.58

Ibutilide

CAS: 122647-31-8

Please enquire for more information about Ibutilide including the price, delivery time and more detailed …

• Formula: C₂₀H₃₆N₂O₃S
• Purity: Min. 95%
• Color and Shape: Clear Liquid
• Molecular weight: 384.58 g/mol