CAS 1226549-39-8

2-PropenaMide, N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]aMino]-6-phenylfuro[2,3-d]pyriMidin-5-yl]phenyl]-

Description:

2-Propenamide, N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]- is a complex organic compound characterized by its unique structural features, including a furo[2,3-d]pyrimidine core and multiple aromatic rings. This compound likely exhibits properties typical of amides, such as the ability to form hydrogen bonds, which can influence its solubility and reactivity. The presence of a hydroxyl group suggests potential for additional hydrogen bonding and may enhance its polarity. The phenyl and furo[2,3-d]pyrimidine moieties contribute to its potential biological activity, possibly making it a candidate for pharmaceutical applications. The stereochemistry indicated by the (1S) configuration suggests specific spatial arrangements that could affect its interaction with biological targets. Overall, this compound's intricate structure may lead to diverse chemical behaviors, making it of interest in medicinal chemistry and related fields. Further studies would be necessary to elucidate its specific properties and potential applications.

Formula: C₂₉H₂₄N₄O₃

Synonyms:

• 2-PropenaMide, N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]aMino]-6-phenylfuro[2,3-d]pyriMidin-5-yl]phenyl]-
• EGFRIN9,EGFR IN 9
• EGFR-IN-9
• N-{3-[4-(2-hydroxy-1-phenylethylamino)-6-phenylfuro[2,3-d]-pyrimidin-5-yl]phenyl}acrylamide
• N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

EGFR-IN-9

CAS: 1226549-39-8

EGFR-IN-9

Purity: ≥98%

Molecular weight: 476.53g/mol

Ref: 54-BUP14326

EGFR-IN-9

CAS: 1226549-39-8

EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M).

Formula: C₂₉H₂₄N₄O₃

Purity: 99.8%

Color and Shape: Solid

Molecular weight: 476.53

Ref: TM-T11163