CAS 1226781-44-7: Omarigliptin
Description:Omarigliptin is a pharmaceutical compound classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, primarily used in the management of type 2 diabetes mellitus. It functions by enhancing the levels of incretin hormones, which in turn increases insulin secretion and decreases glucagon levels in a glucose-dependent manner. This mechanism helps to improve glycemic control. Omarigliptin is characterized by its long half-life, allowing for once-weekly dosing, which can improve patient adherence to treatment regimens. The compound is typically administered orally and is often used in combination with other antidiabetic medications. In terms of its chemical structure, Omarigliptin features a specific arrangement of atoms that contributes to its biological activity and pharmacokinetic properties. As with any medication, potential side effects may include gastrointestinal disturbances, headache, and risk of hypoglycemia, particularly when used with other glucose-lowering agents. Overall, Omarigliptin represents a significant advancement in diabetes management, offering a convenient dosing schedule and effective glycemic control.
Formula:C17H20F2N4O3S
InChI:InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/m1/s1
InChI key:InChIKey=MKMPWKUAHLTIBJ-ISTRZQFTSA-N
SMILES:O=S(=O)(N1N=C2C(=C1)CN(C2)C3COC(C4=CC(F)=CC=C4F)C(N)C3)C
- Synonyms:
- (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine
- (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine
- 2H-Pyran-3-amine, 2-(2,5-difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-, (2R,3S,5R)-
- Mk-3102
- Omarigliptin
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2H-Pyran-3-amine, 2-(2,5-difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-, (2R,3S,5R)-
Ref: IN-DA0017MJ
1g | 630.00 € | ||
10mg | 56.00 € | ||
50mg | 110.00 € | ||
100mg | 161.00 € | ||
250mg | 189.00 € |
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Ref: 4Z-O-054001
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
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Omarigliptin
Ref: TM-T2316
1mg | 40.00 € | ||
2mg | 52.00 € | ||
5mg | 85.00 € | ||
10mg | 124.00 € | ||
25mg | 212.00 € | ||
50mg | 350.00 € | ||
100mg | 505.00 € | ||
500mg | 1,121.00 € | ||
1mL*10mM (DMSO) | 138.00 € |
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(2R,3S,5R)-2-(2,5-DIFLUOROPHENYL)-5-[2-(METHYLSULFONYL)-2,6-DIHYDROPYRROLO[3,4-C]PYRAZOL-5(4H)-YL]TETRAHYDRO-2H-PYRAN-3-AMINE
Ref: 10-F475475
5g | To inquire |
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(2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine
Ref: 3D-FD103522
25g | Discontinued | Request information | |
50g | Discontinued | Request information | |
100mg | Discontinued | Request information | |
250mg | Discontinued | Request information | |
500mg | Discontinued | Request information |