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Omarigliptin

CAS 1226781-44-7: Omarigliptin

Description:Omarigliptin is a pharmaceutical compound classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, primarily used in the management of type 2 diabetes mellitus. It functions by enhancing the levels of incretin hormones, which in turn increases insulin secretion and decreases glucagon levels in a glucose-dependent manner. This mechanism helps to improve glycemic control. Omarigliptin is characterized by its long half-life, allowing for once-weekly dosing, which can improve patient adherence to treatment regimens. The compound is typically administered orally and is often used in combination with other antidiabetic medications. In terms of its chemical structure, Omarigliptin features a specific arrangement of atoms that contributes to its biological activity and pharmacokinetic properties. As with any medication, potential side effects may include gastrointestinal disturbances, headache, and risk of hypoglycemia, particularly when used with other glucose-lowering agents. Overall, Omarigliptin represents a significant advancement in diabetes management, offering a convenient dosing schedule and effective glycemic control.

Formula:C17H20F2N4O3S

InChI:InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/m1/s1

InChI key:InChIKey=MKMPWKUAHLTIBJ-ISTRZQFTSA-N

SMILES:O=S(=O)(N1N=C2C(=C1)CN(C2)C3COC(C4=CC(F)=CC=C4F)C(N)C3)C

  • Synonyms:
  • (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine
  • (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine
  • 2H-Pyran-3-amine, 2-(2,5-difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-, (2R,3S,5R)-
  • Mk-3102
  • Omarigliptin
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2H-Pyran-3-amine, 2-(2,5-difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-, (2R,3S,5R)-

CAS:1226781-44-7

Ref: IN-DA0017MJ

1g630.00 €
10mg56.00 €
50mg110.00 €
100mg161.00 €
250mg189.00 €
Estimated delivery in United States, on Tuesday 4 Mar 2025
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Ref: 4Z-O-054001

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Omarigliptin

CAS:1226781-44-7

Ref: TM-T2316

1mg40.00 €
2mg52.00 €
5mg85.00 €
10mg124.00 €
25mg212.00 €
50mg350.00 €
100mg505.00 €
500mg1,121.00 €
1mL*10mM (DMSO)138.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
discount label

(2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine

CAS:1226781-44-7

Ref: 3D-FD103522

25gDiscontinuedRequest information
50gDiscontinuedRequest information
100mgDiscontinuedRequest information
250mgDiscontinuedRequest information
500mgDiscontinuedRequest information
Discontinued product
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