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CAS 1226781-44-7

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Omarigliptin

Description:
Omarigliptin is a pharmaceutical compound classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, primarily used in the management of type 2 diabetes mellitus. It functions by enhancing the levels of incretin hormones, which in turn increases insulin secretion and decreases glucagon levels in a glucose-dependent manner. This mechanism helps to improve glycemic control. Omarigliptin is characterized by its long half-life, allowing for once-weekly dosing, which can improve patient adherence to treatment regimens. The compound is typically administered orally and is often used in combination with other antidiabetic medications. In terms of its chemical structure, Omarigliptin features a specific arrangement of atoms that contributes to its biological activity and pharmacokinetic properties. As with any medication, potential side effects may include gastrointestinal disturbances, headache, and risk of hypoglycemia, particularly when used with other glucose-lowering agents. Overall, Omarigliptin represents a significant advancement in diabetes management, offering a convenient dosing schedule and effective glycemic control.
Formula:C17H20F2N4O3S
InChI:InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/m1/s1
InChI key:InChIKey=MKMPWKUAHLTIBJ-ISTRZQFTSA-N
SMILES:S(C)(=O)(=O)N1C=C2C(CN(C2)[C@@H]3C[C@H](N)[C@H](OC3)C4=C(F)C=CC(F)=C4)=N1
Synonyms:
  • (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine
  • (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine
  • 2H-Pyran-3-amine, 2-(2,5-difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-, (2R,3S,5R)-
  • Mk-3102
  • Omarigliptin
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Found 6 products.