CAS 1226895-20-0

ATB 346

Description:

ATB-346, with the CAS number 1226895-20-0, is a novel chemical compound that has garnered attention for its potential therapeutic applications, particularly in the context of anti-inflammatory and analgesic effects. It is a prodrug of a non-steroidal anti-inflammatory drug (NSAID), designed to minimize gastrointestinal side effects commonly associated with traditional NSAIDs. The compound is characterized by its ability to selectively inhibit cyclooxygenase enzymes, which play a crucial role in the inflammatory process. ATB-346 is notable for its improved safety profile, as it is metabolized into its active form in the body, allowing for effective pain relief while reducing the risk of adverse effects. Additionally, its pharmacokinetic properties suggest a favorable absorption and distribution in biological systems, making it a candidate for further clinical evaluation. Research into ATB-346 continues to explore its efficacy and safety in various inflammatory conditions, highlighting its potential as a significant advancement in pain management therapies.

2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, 4-(aminothioxomethyl)phenyl ester

CAS: 1226895-20-0

Formula: C₂₁H₁₉NO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 365.4455

Ref: IN-DA000J01

Otenaproxesul

CAS: 1226895-20-0

Otenaproxesul

Purity: ≥95%

Molecular weight: 365.45g/mol

Ref: 54-BUP09656

Otenaproxesul

CAS: 1226895-20-0

Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.

Formula: C₂₁H₁₉NO₃S

Purity: 98.76% - 99.13%

Color and Shape: Solid

Molecular weight: 365.45

Ref: TM-T1867

ATB-346

CAS: 1226895-20-0

Purity: 95.0%

Molecular weight: 365.45

Ref: 10-F468323

ATB 346

CAS: 1226895-20-0

ATB 346 is a nonsteroidal anti-inflammatory drug that works by inhibiting cyclooxygenase (COX) and lipoxygenase enzymes. It has been shown to inhibit COX-2, which is involved in the production of prostaglandin E2 and thromboxane A2, and is thought to be responsible for the inflammatory response. ATB 346 has been demonstrated to reduce inflammation in an experimental model of abdominal surgery in rats. This drug also inhibits the release of histamine and other proinflammatory substances by blocking the activity of neurotrophic factors such as nerve growth factor or brain-derived neurotrophic factor.

Formula: C₂₁H₁₉NO₃S

Purity: Min. 95%

Molecular weight: 365.45 g/mol

Ref: 3D-BZB89520