CAS 1227158-85-1

1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine

Description:

1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine, with CAS number 1227158-85-1, is a complex organic compound characterized by its multi-cyclic structure and the presence of various functional groups. This substance features a cyclopropyl ring, which contributes to its unique steric and electronic properties. The molecule also contains a piperazine moiety, known for its biological activity, and a pyridine ring, which can enhance solubility and reactivity. Additionally, the presence of a trifluoromethoxy group suggests potential for increased lipophilicity and metabolic stability. The oxadiazole and pyrazole components are often associated with pharmacological activity, making this compound of interest in medicinal chemistry. Overall, its intricate structure may confer specific interactions with biological targets, potentially leading to therapeutic applications. However, detailed studies would be necessary to fully elucidate its properties and biological effects.

Formula: C₂₆H₂₆F₃N₇O₂

InChI: InChI=1S/C26H26F3N7O2/c1-17-14-22(25-31-24(33-38-25)19-2-6-21(7-3-19)37-26(27,28)29)32-36(17)16-18-8-9-30-23(15-18)35-12-10-34(11-13-35)20-4-5-20/h2-3,6-9,14-15,20H,4-5,10-13,16H2,1H3

InChI key: InChIKey=CDJNNOJINJAXPV-UHFFFAOYSA-N

SMILES: C(N1N=C(C2=NC(=NO2)C3=CC=C(OC(F)(F)F)C=C3)C=C1C)C=4C=C(N=CC4)N5CCN(CC5)C6CC6

Synonyms:

• 1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine
• Piperazine, 1-cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]-
• BAY 87-2243

BAY 87-2243

CAS: 1227158-85-1

Formula: C₂₆H₂₆F₃N₇O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 525.5255

Ref: IN-DA009C99

5-(1-((2-(4-Cyclopropylpiperazin-1-Yl)Pyridin-4-Yl)Methyl)-5-Methyl-1H-Pyrazol-3-Yl)-3-(4-(Trifluoromethoxy)Phenyl)-1,2,4-Oxadiazole

CAS: 1227158-85-1

5-(1-((2-(4-Cyclopropylpiperazin-1-Yl)Pyridin-4-Yl)Methyl)-5-Methyl-1H-Pyrazol-3-Yl)-3-(4-(Trifluoromethoxy)Phenyl)-1,2,4-Oxadiazole

Purity: 99%

Molecular weight: 525.53g/mol

Ref: 54-PC108455

BAY 87-2243

CAS: 1227158-85-1

BAY 87-2243

Purity: ≥98%

Molecular weight: 525.53g/mol

Ref: 54-BUP12945

BAY 87-2243

CAS: 1227158-85-1

BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).

Formula: C₂₆H₂₆F₃N₇O₂

Purity: 98% - 99.95%

Color and Shape: Solid

Molecular weight: 525.53

Ref: TM-T2488

BAY 87-2243

Controlled Product

CAS: 1227158-85-1

Formula: C₂₆H₂₆F₃N₇O₂

Color and Shape: Neat

Molecular weight: 525.525

Ref: TR-B119070

BAY 87-2243-d8

Controlled Product

CAS: 1227158-85-1

Formula: C₂₆D₈H₁₈F₃N₇O₂

Color and Shape: Neat

Molecular weight: 533.575

Ref: TR-B119072