CAS 1227162-75-5

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide

Controlled Product

CAS: 1227162-75-5

Applications N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),

Formula: C₁₈H₂₂N₂O

Color and Shape: Neat

Molecular weight: 282.38

Ref: TR-A795305

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-naphthalenecarboxamide

CAS: 1227162-75-5

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-naphthalenecarboxamide is a research tool that can be used as an activator or ligand to study protein interactions in cell biology and pharmacology. It has been reported to inhibit the activity of ion channels, such as voltage gated potassium channels and calcium channels. N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-naphthalenecarboxamide also blocks the binding of antibodies to cells and peptides in vitro, which may be due to its ability to inhibit protein synthesis. This chemical is listed on CAS Registry Number 1227162-75-5 and has a purity of >99%.

Formula: C₁₈H₂₂N₂O

Purity: Min. 95%

Molecular weight: 282.4 g/mol

Ref: 3D-CZB16275

Dehydro Palonosetron

CAS: 1227162-75-5

Formula: C₁₈H₂₂N₂O

Molecular weight: 282.39

Ref: ST-EA-CP-P14009