CAS 1227603-79-3

3-Chloro-5-fluoro-pyridine-4-carbaldehyde

CAS: 1227603-79-3

Formula: C₆H₃ClFNO

Purity: 95%

Molecular weight: 159.5455

Ref: IN-DA009XID

3-Chloro-5-fluoroisonicotinaldehyde

CAS: 1227603-79-3

Purity: ≥95%

Molecular weight: 159.5399933

Ref: 10-F776453

3-Chloro-5-fluoroisonicotinaldehyde

CAS: 1227603-79-3

3-Chloro-5-fluoroisonicotinaldehyde is a prostaglandin analogue that inhibits the production of prostaglandin E2. Prostaglandin E2 synthesis is initiated by the enzyme cyclooxygenase. The inhibition of this enzyme causes an increase in the concentration of arachidonic acid, which leads to an increase in the production of prostaglandin E2. 3-Chloro-5-fluoroisonicotinaldehyde has been shown to be a potent inhibitor of Cox-1 and Cox-2 enzymes. It also has low metabolic stability and low oral bioavailability. This drug is being investigated for its potential as an analgesic with improved side effect profile, and for its potential as a novel therapeutic agent for inflammatory diseases such as rheumatoid arthritis.

Formula: C₆H₃ClFNO

Purity: Min. 95%

Molecular weight: 159.54 g/mol

Ref: 3D-CZB60379