CAS 1228079-74-0

2-Amino-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-5-one

CAS: 1228079-74-0

2-Amino-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-5-one is a drug that has been shown to have immune modulating and anticancer effects. It has been found to inhibit the proliferation of cells in culture and to suppress the growth of cancer cells in rodent models. The compound has also been shown to have antiviral activity against human cytomegalovirus (HCMV) and influenza virus. 2-Amino-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-5-one binds with high affinity to heat shock protein 90 (hsp90), an enzyme that is involved in signaling pathways that regulate cell proliferation. This binding inhibits the activation of hsp90 by proteases such as calpain or cathepsin B and prevents the release of proapoptotic proteins from

Formula: C₇H₈N₄O

Purity: Min. 95%

Molecular weight: 164.16 g/mol

Ref: 3D-DZB07974