CAS 122855-43-0

pacidamycin 5

Description:

Pacidamycin 5, identified by its CAS number 122855-43-0, is a member of the pacidamycin family, which are antibiotics derived from microbial sources. This compound exhibits a complex structure characterized by a bicyclic core that is typical of many natural products. Pacidamycin 5 is known for its antibacterial properties, particularly against certain Gram-positive bacteria, making it of interest in the field of medicinal chemistry and antibiotic development. Its mechanism of action involves inhibition of bacterial protein synthesis, which is crucial for bacterial growth and replication. Additionally, pacidamycin derivatives often display a range of biological activities, including potential antitumor effects. The stability, solubility, and bioavailability of pacidamycin 5 can vary, influencing its therapeutic applications. Research continues to explore its efficacy and safety profile, as well as potential modifications to enhance its pharmacological properties. Overall, pacidamycin 5 represents a significant compound in the ongoing search for effective antimicrobial agents.

Formula: C₃₆H₄₄N₈O₁₁

InChI: InChI=1/C36H44N8O11/c1-19(37)27(46)17-26(42(2)31(49)24(38)14-21-9-6-10-22(45)13-21)30(39)32(50)44(35(53)40-25(34(51)52)15-20-7-4-3-5-8-20)18-23-16-28(47)33(55-23)43-12-11-29(48)41-36(43)54/h3-13,18-19,24-26,28,30,33,45,47H,14-17,37-39H2,1-2H3,(H,40,53)(H,51,52)(H,41,48,54)/b23-18+/t19-,24-,25?,26?,28?,30?,33?/m0/s1

Synonyms:

• Butanamide, N-(((1-carboxy-2-phenylethyl)amino)carbonyl)alanyl-N-((5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene)methyl)-N3-(3-hydroxyphenylalanyl)-N3-methyl-2,3-diamino-
• 3,5,8,11-Tetraazatetradecanoic acid, 13-amino-9-[[[(Z)-[(4R,5R)-5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene]methyl]amino]carbonyl]-14-(3-hydroxyphenyl)-6,10,11-trimethyl-4,7,12-trioxo-2-(phenylmethyl)-, (2S,6S,9S,10S,13S)-
• Pacidamycin 5
• N-({(6S)-2,6-diamino-3-[(3-hydroxy-L-phenylalanyl)(methyl)amino]-5-oxoheptanoyl}{(E)-[5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxydihydrofuran-2(3H)-ylidene]methyl}carbamoyl)phenylalanine
• pacidamycin 5

Pacidamycin 5

CAS: 122855-43-0

Pacidamycin 5 exhibits inhibitory effects on Pseudomonas aeruginosa. It is also effective against certain strains of Staphylococcus aureus and Escherichia coli.

Formula: C₃₆H₄₄N₈O₁₁

Color and Shape: Solid

Molecular weight: 764.782

Ref: TM-TN10472