CAS 1228567-12-1

(αR)-α-(Methyl-d3)-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine

Description:

The chemical substance known as (αR)-α-(Methyl-d3)-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, with the CAS number 1228567-12-1, is a synthetic compound that belongs to the class of naphthalenes and amines. This compound features a naphthalene moiety, which contributes to its aromatic characteristics, and a trifluoromethyl group that enhances its lipophilicity and may influence its biological activity. The presence of deuterium in the methyl group indicates isotopic labeling, which can be useful in studies involving metabolic pathways or pharmacokinetics. The compound's structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific receptors or pathways. Its unique combination of functional groups may also impart specific physicochemical properties, such as solubility and stability, which are critical for its efficacy in biological systems. Overall, this compound represents a complex structure with potential implications in drug design and development.

Formula: C₂₂H₁₉D₃F₃N

InChI: InChI=1S/C22H22F3N/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3/t16-/m1/s1/i1D3

InChI key: InChIKey=VDHAWDNDOKGFTD-JOTALGBPSA-N

SMILES: [C@@H](NCCCC1=CC(C(F)(F)F)=CC=C1)(C([2H])([2H])[2H])C=2C3=C(C=CC2)C=CC=C3

Synonyms:

• 1-Naphthalenemethanamine, α-(methyl-d3)-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)-
• (αR)-α-(Methyl-d3)-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine

Cinacalcet-d3 HCl

CAS: 1228567-12-1

Formula: C₂₂H₁₉D₃F₃N·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 360.44 36.46

Ref: 4Z-C-402

(R)-Cinacalcet-d3

CAS: 1228567-12-1

(R)-Cinacalcet-d3 is a medicinal compound that functions as an inhibitor of kinase activity. It has been shown to induce apoptosis in human cancer cells, making it a promising candidate for anticancer therapy. This compound is structurally similar to cinacalcet, a drug used to treat hyperparathyroidism and secondary hyperparathyroidism. (R)-Cinacalcet-d3 can be used as an analog for studying the effects of cinacalcet on protein function and signaling pathways in cancer cells. In vitro studies have demonstrated that this compound inhibits luciferase activity in Chinese hamster ovary cells, suggesting that it may have potential as an anticancer agent. Further research is needed to determine the full potential of (R)-Cinacalcet-d3 in treating tumors and other forms of cancer.

Formula: C₂₂H₂₂F₃N

Purity: Min. 95%

Molecular weight: 360.4 g/mol

Ref: 3D-DZB56712