CAS 122883-93-6: Ziprasidone hydrochloride
Description:Ziprasidone hydrochloride is an atypical antipsychotic medication primarily used in the treatment of schizophrenia and bipolar disorder. It functions as a serotonin-dopamine antagonist, influencing neurotransmitter activity in the brain to help manage symptoms of these mental health conditions. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its formulation for oral and injectable administration. Its chemical structure includes a piperazine ring, contributing to its pharmacological properties. Ziprasidone is known for its relatively low propensity to cause weight gain compared to other antipsychotics, making it a preferred option for some patients. However, it may be associated with side effects such as sedation, dizziness, and potential cardiovascular effects, including QT interval prolongation. As with any medication, it is essential for patients to be monitored for efficacy and adverse reactions during treatment.
Formula:C21H21ClN4OS·ClH
InChI:InChI=1S/C21H21ClN4OS.ClH/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21;/h1-4,11,13H,5-10,12H2,(H,23,27);1H
InChI key:InChIKey=NZDBKBRIBJLNNT-UHFFFAOYSA-N
SMILES:Cl.O=C1NC2=CC(Cl)=C(C=C2C1)CCN3CCN(C4=NSC=5C=CC=CC54)CC3
- Synonyms:
- 2H-Indol-2-one,5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-,monohydrochloride
- 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride
- 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)ethyl]-6-chloro-1,3-dihydro-2H-indol-2-onehydrochloride
- Azona
- Cp 88059-1
- Zeldox
- Ziprasidone hydrochloride
- Zipsydon
- 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride (1:1)