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CAS 122889-11-6

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Fmoc-D-Ser(Bzl)-OH

Description:
Fmoc-D-Ser(Bzl)-OH, with the CAS number 122889-11-6, is a chemical compound commonly used in peptide synthesis and research. It is a derivative of serine, an amino acid, and features a fluorenylmethyloxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis to protect the amino group during the coupling reactions. The compound also contains a benzyl (Bzl) side chain attached to the hydroxyl group of the serine, enhancing its hydrophobic properties and providing additional functionality for further chemical modifications. Fmoc-D-Ser(Bzl)-OH is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane, but less soluble in water. Its stability under standard laboratory conditions makes it a valuable intermediate in the synthesis of more complex peptides and proteins. Proper handling and storage are essential, as with many chemical substances, to maintain its integrity and reactivity.
Formula:C25H23NO5
InChI:InChI=1S/C25H23NO5/c27-24(28)23(16-30-14-17-8-2-1-3-9-17)26-25(29)31-15-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2,(H,26,29)(H,27,28)/t23-/m1/s1
InChI key:DYBDGLCDMLNEMJ-HSZRJFAPSA-N
SMILES:C1=CC=C(C=C1)COC[C@H](C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Synonyms:
  • N-Fmoc-O-benzyl-D-serine
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