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CAS 1228960-69-7

:

MLN0905

Description:
MLN0905, also known by its CAS number 1228960-69-7, is a small molecule that functions primarily as a selective inhibitor of the enzyme protein kinase mTOR (mechanistic target of rapamycin). This compound is notable for its role in modulating cellular processes such as growth, proliferation, and survival, making it of interest in cancer research and therapeutic development. MLN0905 exhibits a specific binding affinity for mTOR, which is part of a critical signaling pathway involved in cell metabolism and growth regulation. The compound's structure typically includes features that facilitate its interaction with the ATP-binding site of the kinase, thereby inhibiting its activity. In preclinical studies, MLN0905 has shown potential in various cancer models, highlighting its importance in the exploration of targeted therapies. As with many kinase inhibitors, the pharmacokinetics, bioavailability, and potential side effects are crucial factors that are evaluated during its development for clinical use.
Synonyms:
  • PLK1 Inhibitor
  • 2-[[5-[3-(Dimethylamino)propyl]-2-methyl-3-pyridinyl]amino]-5,7-dihydro-9-(trifluoromethyl)- 6H-pyrimido[5,4-d][1]benzazepine-6-thione
  • 6H-Pyrimido[5,4-d][1]benzazepine-6-thione, 2-[[5-[3-(dimethylamino)propyl]-2-methyl-3-pyridinyl]amino]-5,7-dihydro-9-(trifluoromethyl)-
  • MLN-0905
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Found 4 products.
  • MLN0905

    CAS:
    Formula:C24H25F3N6S
    Purity:97%
    Color and Shape:Solid
    Molecular weight:486.5557

    Ref: IN-DA009CDH

    1mg
    86.00€
    2mg
    109.00€
    5mg
    213.00€
    10mg
    194.00€
    25mg
    622.00€
    50mg
    To inquire
    100mg
    To inquire
  • MLN0905

    CAS:
    MLN0905
    Purity:≥95%
    Molecular weight:486.56g/mol

    Ref: 54-BUP07982

    1mg
    87.00€
    5mg
    185.00€
    10mg
    273.00€
    25mg
    499.00€
    50mg
    738.00€
  • MLN0905

    CAS:
    MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).
    Formula:C24H25F3N6S
    Purity:98% - 99.92%
    Color and Shape:Solid
    Molecular weight:486.56
  • MLN 0905

    CAS:
    <p>Inhibitor of Polo-like kinase 1</p>
    Formula:C24H25F3N6S
    Purity:Min. 95%
    Molecular weight:486.56 g/mol

    Ref: 3D-FM103928

    1mg
    170.00€
    2mg
    244.00€
    5mg
    478.00€
    10mg
    668.00€
    25mg
    1,085.00€