CAS 1228960-69-7: MLN0905

Description: MLN0905, also known by its CAS number 1228960-69-7, is a small molecule that functions primarily as a selective inhibitor of the enzyme protein kinase mTOR (mechanistic target of rapamycin). This compound is notable for its role in modulating cellular processes such as growth, proliferation, and survival, making it of interest in cancer research and therapeutic development. MLN0905 exhibits a specific binding affinity for mTOR, which is part of a critical signaling pathway involved in cell metabolism and growth regulation. The compound's structure typically includes features that facilitate its interaction with the ATP-binding site of the kinase, thereby inhibiting its activity. In preclinical studies, MLN0905 has shown potential in various cancer models, highlighting its importance in the exploration of targeted therapies. As with many kinase inhibitors, the pharmacokinetics, bioavailability, and potential side effects are crucial factors that are evaluated during its development for clinical use.

Synonyms:

• PLK1 Inhibitor
• 2-[[5-[3-(Dimethylamino)propyl]-2-methyl-3-pyridinyl]amino]-5,7-dihydro-9-(trifluoromethyl)- 6H-pyrimido[5,4-d][1]benzazepine-6-thione
• 6H-Pyrimido[5,4-d][1]benzazepine-6-thione, 2-[[5-[3-(dimethylamino)propyl]-2-methyl-3-pyridinyl]amino]-5,7-dihydro-9-(trifluoromethyl)-
• MLN-0905

MLN0905

CAS: 1228960-69-7

• Formula: C₂₄H₂₅F₃N₆S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 486.5557095999999

MLN0905

CAS: 1228960-69-7

• Purity: ≥95%
• Molecular weight: 486.56g/mol

MLN0905

CAS: 1228960-69-7

MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).

• Formula: C₂₄H₂₅F₃N₆S
• Purity: 97.17% - 98%
• Color and Shape: Solid
• Molecular weight: 486.56

MLN 0905

CAS: 1228960-69-7

Inhibitor of Polo-like kinase 1

• Formula: C₂₄H₂₅F₃N₆S
• Purity: Min. 95%
• Molecular weight: 486.56 g/mol