CAS 122898-67-3: Itopride

Description: Itopride is a synthetic compound primarily used as a gastroprokinetic agent, which means it enhances gastrointestinal motility. Its chemical structure features a piperidine ring, contributing to its pharmacological properties. Itopride acts as a dopamine D2 receptor antagonist and also inhibits acetylcholinesterase, leading to increased levels of acetylcholine, which promotes gastrointestinal movement. This dual action makes it effective in treating conditions like functional dyspepsia and gastroesophageal reflux disease (GERD). The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Itopride is known for its relatively favorable safety profile, with common side effects including gastrointestinal disturbances. Its mechanism of action and therapeutic uses make it a valuable option in managing motility disorders. As with any medication, it is essential to use it under medical supervision to ensure safety and efficacy.

Formula: C₂₀H₂₆N₂O₄

InChI: InChI=1S/C20H26N2O4/c1-22(2)11-12-26-17-8-5-15(6-9-17)14-21-20(23)16-7-10-18(24-3)19(13-16)25-4/h5-10,13H,11-12,14H2,1-4H3,(H,21,23)

InChI key: InChIKey=QQQIECGTIMUVDS-UHFFFAOYSA-N

SMILES: O=C(NCC1=CC=C(OCCN(C)C)C=C1)C2=CC=C(OC)C(OC)=C2

Synonyms:

• 122898-67-3
• Benzamide, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy-
• Itopride Base
• N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxybenzamide
• N-{4-[2-(Dimethylamino)ethoxy]benzyl}-3,4-dimethoxybenzamide
• Itopride

Benzamide, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy-

CAS: 122898-67-3

• Formula: C₂₀H₂₆N₂O₄
• Molecular weight: 358.4314

Itopride

CAS: 122898-67-3

• Formula: C₂₀H₂₆N₂O₄
• Molecular weight: 358.43

Itopride Hydrochloride

CAS: 122892-31-3 122898-67-3

• Formula: C₂₀H₂₆N₂O₄·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 394.90

Itopride free base

CAS: 122898-67-3

Itopride HCl combats dyspepsia and GERD, inhibiting AChE and blocking D2 receptors.

• Formula: C₂₀H₂₆N₂O₄
• Color and Shape: White
• Molecular weight: 358.43