CAS 1229-29-4
:Doxepin hydrochloride
Description:
Doxepin hydrochloride is a tricyclic antidepressant primarily used to treat depression and anxiety disorders, as well as insomnia. It functions by inhibiting the reuptake of neurotransmitters such as norepinephrine and serotonin, thereby enhancing mood and promoting sleep. This compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Doxepin hydrochloride exhibits a relatively long half-life, allowing for once-daily dosing in many cases. Its pharmacological effects can include sedation, which is beneficial for patients with sleep disturbances. However, it may also lead to side effects such as dry mouth, dizziness, and weight gain. Due to its anticholinergic properties, caution is advised in patients with certain pre-existing conditions, such as glaucoma or urinary retention. Overall, doxepin hydrochloride is a versatile medication with a well-established profile in the management of mood and sleep disorders.
Formula:C19H21NO·ClH
InChI:InChI=1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H
InChI key:InChIKey=MHNSPTUQQIYJOT-UHFFFAOYSA-N
SMILES:C(CCN(C)C)=C1C=2C(COC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:- (3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride
- (3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride
- 1-Propanamine, 3-(dibenz[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
- 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride
- 11-(3-Dimethylaminopropylidene)-6,11-Dihydro-Benz[B,E]Oxepin Hcl
- 3-(6,11-Dihydrodibenz(B,E)Oxepin-11-Ylidene)Propyldimethylamine Hcl
- 3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
- Adapin
- Aponal
- Curatin
- Dibenz[b,e]oxepin, 1-propanamine deriv.
- Dibenz[b,e]oxepin-Δ<sup>11(6</sup><sup>H</sup><sup>),γ</sup>-propylamine, N,N-dimethyl-, hydrochloride
- Doxepin Hydrochloride
- Doxepine hydrochloride
- N,N-Dimethyldibenz[b,e]oxepin-Δ<sup>11(6</sup><sup>H</sup><sup>),γ</sup>-propylamine hydrochloride
- P 3693A
- Quitaxon
- Silenor
- Sinequan
- Sinequin
- DOXEPINONE HCl
- See more synonyms
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
Doxepin hydrochloride (Standard)
CAS:Doxepin hydrochloride (Standard) is the standard substance of Doxepin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.Formula:C19H22ClNOMolecular weight:315.837Doxepin Hydrochloride
CAS:Controlled ProductStability Hygroscopic
Applications Doxepin is used clinically to treat anxiety and depression. Doxepin is an antidepressant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ribbentrop, A., et al.: Arzneim.-Forsch., 15, 863 (1965); Hobbs, D.C., et al.: Biochem. Pharmacol., 18, 1941 (1969); Pinder, R.M., et al.: Drugs, 13, 161 (1977); Shrivastava, R.K., et al.: Clin. Ther., 7, 181 (1985);Formula:C19H21NO·ClHColor and Shape:NeatMolecular weight:315.84Doxepin-13C, d3 .xHydrochloride
CAS:Controlled ProductFormula:C18CH18D3NO•x(HCl)Color and Shape:NeatMolecular weight:319.8Doxepin HCl - Bio-X ™
CAS:Controlled ProductDoxepin is a psychotropic agent that is used in the treatment of depression, anxiety and insomnia. This drug has antidepressant and anxiolytic properties. This mechanism of action for this drug is not clear however it is known to be a histamine receptor antagonist.Formula:C19H21NO•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:315.84 g/mol1-Propanamine, 3-(dibenz[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
CAS:Purity:99%+(HPLC);RGMolecular weight:315.84Doxepin hydrochloride
CAS:Controlled ProductHistamine receptor H1 antagonist; tricyclic antidepressantFormula:C19H22ClNOPurity:Min. 95%Color and Shape:PowderMolecular weight:315.84 g/mol
