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CAS 1229-35-2

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Methdilazine hydrochloride

Description:
Methdilazine hydrochloride is an antihistamine belonging to the phenothiazine class, primarily used for its antiemetic and antihistaminic properties. It is characterized by its ability to block H1 histamine receptors, which helps alleviate allergic reactions and symptoms such as itching, sneezing, and runny nose. The compound is typically administered in the form of its hydrochloride salt, which enhances its solubility in water, making it suitable for oral or parenteral administration. Methdilazine hydrochloride exhibits a moderate to high lipophilicity, allowing it to cross biological membranes effectively. Its pharmacological profile includes sedative effects, which can be beneficial in treating motion sickness and as a premedication for surgical procedures. However, like other antihistamines, it may cause side effects such as drowsiness, dry mouth, and dizziness. The substance is subject to regulatory controls, and its use should be guided by medical advice to ensure safety and efficacy.
Formula:C18H20N2S·ClH
InChI:InChI=1S/C18H20N2S.ClH/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)20;/h2-9,14H,10-13H2,1H3;1H
InChI key:InChIKey=IEISBKIVLDXSMZ-UHFFFAOYSA-N
SMILES:C(N1C=2C(SC=3C1=CC=CC3)=CC=CC2)C4CN(C)CC4.Cl
Synonyms:
  • 10-((1-Methyl-3-pyrrolidinyl)methyl)phenothiazine monohydrochloride
  • 10-((1-Methyl-3-pyrrolidinyl)methyl)phenothiazine, hydrochloride
  • 10-(1-Methyl-3-pyrroldiylmethyl)phenothiazine hydrochloride
  • 10-[(1-methylpyrrolidin-3-yl)methyl]-10H-phenothiazine
  • 10-[(1-methylpyrrolidin-3-yl)methyl]-10H-phenothiazine hydrochloride (1:1)
  • 10H-Phenothiazine, 10-((1-methyl-3-pyrrolidinyl)methyl)-, monohydrochloride
  • 10H-Phenothiazine, 10-[(1-methyl-3-pyrrolidinyl)methyl]-, hydrochloride (1:1)
  • Bristaline
  • Ccris 6256
  • Dilosyn
  • See more synonyms
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