CAS 1229096-88-1

GSK9027

CAS: 1229096-88-1

GSK9027

Purity: ≥98%

Molecular weight: 525.52g/mol

Ref: 54-BUP03889

GSK 9027

CAS: 1229096-88-1

GSK 9027 is a conjugate of the chemotherapeutic agent gemcitabine with an antisense oligodeoxynucleotide. The conjugate selectively targets prostate cancer cells and inhibits their growth without affecting normal cells. GSK 9027 has been shown to inhibit the expression of genes that are necessary for growth and proliferation, such as cyclin D1 and c-myc, in pancreatic cancer cells. It also has antitumor activity against infectious diseases, including cytomegalovirus infection in mice. GSK 9027 is currently being studied for use in inflammatory diseases, like rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, and Alzheimer's disease.

Formula: C₂₇H₁₉F₄N₃O₂S

Purity: Min. 95%

Molecular weight: 525.5 g/mol

Ref: 3D-EZB09688

GSK9027

CAS: 1229096-88-1

GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than dexamethasone.

Formula: C₂₇H₁₉F₄N₃O₂S

Purity: 99.31%

Color and Shape: Solid

Molecular weight: 525.52

Ref: TM-T22818