CAS 122956-68-7

Modipafant racemate

Description:

Modipafant racemate, with the CAS number 122956-68-7, is a chemical compound that belongs to the class of substances known as antagonists of the platelet-activating factor (PAF). It is primarily studied for its potential therapeutic applications, particularly in conditions related to inflammation and cardiovascular diseases. The racemic mixture indicates that it contains equal amounts of two enantiomers, which may exhibit different biological activities. Modipafant has been investigated for its ability to inhibit PAF-induced responses, which can include platelet aggregation and bronchoconstriction. Its pharmacological profile suggests that it may have anti-inflammatory properties, making it a candidate for research in various medical fields. However, as with many compounds, the specific characteristics such as solubility, stability, and bioavailability can vary and are critical for its application in clinical settings. Further studies are necessary to fully understand its mechanisms of action and potential side effects.

Formula: C₃₄H₂₉ClN₆O₃

InChI: InChI=1/C34H29ClN6O3/c1-4-44-34(43)31-30(24-9-5-6-10-25(24)35)29(33(42)40-28-11-7-8-17-37-28)20(2)38-32(31)22-12-14-23(15-13-22)41-21(3)39-26-19-36-18-16-27(26)41/h5-19,30,38H,4H2,1-3H3,(H,37,40,42)/t30-/m1/s1

SMILES: CCOC(=O)C1=C(c2ccc(cc2)n2c(C)nc3cnccc23)NC(=C([C@H]1c1ccccc1Cl)C(=Nc1ccccn1)O)C

Synonyms:

• 3-pyridinecarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-5-[(2-pyridinylamino)carbonyl]-, ethyl ester
• ethyl 4-(2-chlorophenyl)-6-methyl-2-[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-5-(pyridin-2-ylcarbamoyl)-1,4-dihydropyridine-3-carboxylate
• ethyl (4R)-4-(2-chlorophenyl)-6-methyl-2-[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-5-(pyridin-2-ylcarbamoyl)-1,4-dihydropyridine-3-carboxylate

(Rac)-Modipafant

CAS: 122956-68-7

(Rac)-Modipafant

Purity: ≥95%

Molecular weight: 605.09g/mol

Ref: 54-BUP07355

(Rac)-Modipafant

CAS: 122956-68-7

(Rac)-Modipafantis a PAFR antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits.

Formula: C₃₄H₂₉ClN₆O₃

Purity: 97.96% - 98.09%

Color and Shape: Solid

Molecular weight: 605.09

Ref: TM-T28081