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CAS 123040-69-7

:

Azasetron

Description:
Azasetron is a chemical compound classified as a selective serotonin 5-HT3 receptor antagonist, primarily used in the context of pharmacology to prevent nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. Its structure features a bicyclic framework that includes a nitrogen atom, which contributes to its pharmacological activity. Azasetron is known for its ability to block the action of serotonin at the 5-HT3 receptors located in the central nervous system and the gastrointestinal tract, thereby mitigating the emetic response. The compound is typically administered in oral or injectable forms, and its efficacy is often evaluated in clinical settings. Azasetron's safety profile and side effects are similar to those of other 5-HT3 antagonists, which may include headache, constipation, and dizziness. As with many pharmaceuticals, its use is subject to regulatory approval and guidelines, ensuring that it is prescribed appropriately to maximize therapeutic benefits while minimizing risks.
Formula:C17H20ClN3O3
InChI:InChI=1S/C17H20ClN3O3/c1-20-14-7-11(18)6-12(16(14)24-9-15(20)22)17(23)19-13-8-21-4-2-10(13)3-5-21/h6-7,10,13H,2-5,8-9H2,1H3,(H,19,23)
InChI key:InChIKey=WUKZPHOXUVCQOR-UHFFFAOYSA-N
SMILES:C(NC1C2CCN(C1)CC2)(=O)C3=C4C(N(C)C(=O)CO4)=CC(Cl)=C3
Synonyms:
  • 2H-1,4-Benzoxazine-8-carboxamide, N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-
  • Azasetron
  • Azasetron HCl
  • N-(1-AZABICYCLO[2.2.2]OCT-3-YL)-6-CHLORO-4-METHYL-3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-8-CARBOXAMIDE hydrochloride
  • N-(1-Azabicyclo[2.2.2]Octan-8-Yl)-6-Chloro-4-Methyl-3-Oxo-1,4-Benzoxazine-8-Carboxamide Hydrochloride
  • N-(1-azabicyclo[2.2.2]oct-3-yl)-6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide hydrochloride (1:1)
  • N-1-Azabicyclo[2.2.2]Oct-3-Yl-6-Chloro-3,4-Dihydro-4-Methyl-3-Oxo-2H-1,4-Benzoxazine-8-Carboxamide Hydrochloride
  • N-1-Azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide
  • Nazasetron
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Found 3 products.