CAS 123050-98-6

(R)-O-Desmethyl Naproxen

Description:

(R)-O-Desmethyl Naproxen is a chiral derivative of naproxen, a nonsteroidal anti-inflammatory drug (NSAID) commonly used for pain relief and inflammation reduction. This compound is characterized by its specific stereochemistry, which influences its pharmacological activity and interactions within biological systems. It typically exhibits anti-inflammatory and analgesic properties, similar to its parent compound, but may differ in potency and side effects due to its unique molecular configuration. The presence of the "O-Desmethyl" designation indicates that it has undergone a demethylation process, affecting its solubility and metabolic pathways. The compound is often studied for its potential therapeutic applications and safety profile, particularly in comparison to other NSAIDs. Its CAS number, 123050-98-6, serves as a unique identifier for regulatory and research purposes. As with many pharmaceuticals, understanding the characteristics of (R)-O-Desmethyl Naproxen is crucial for its application in clinical settings and for the development of new therapeutic agents.

Formula: C₁₃H₁₂O₃

InChI: InChI=1/C13H12O3/c1-8(13(15)16)9-2-3-11-7-12(14)5-4-10(11)6-9/h2-8,14H,1H3,(H,15,16)/t8-/m1/s1

SMILES: C[C@H](c1ccc2cc(ccc2c1)O)C(=O)O

Synonyms:

• (aR)-6-Hydroxy-α-methyl-2-naphthaleneacetic Acid
• (R)-2-(6-Hydroxy-2-naphthyl)propionic Acid
• (R)-O-Desmethyl Naproxen

2-Naphthaleneacetic acid, 6-hydroxy-α-methyl-, (αR)-

CAS: 123050-98-6

Formula: C₁₃H₁₂O₃

Color and Shape: Solid

Molecular weight: 216.2326

Ref: IN-DA000K0M

(R)-O-Desmethyl Naproxen

CAS: 123050-98-6

Formula: C₁₃H₁₂O₃

Molecular weight: 216.24

Ref: 4Z-N-2321

(R)-O-Desmethyl Naproxen

Controlled Product

CAS: 123050-98-6

Applications A metabolite of Naproxen.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rettie, A., et al.: Chem. Res. Toxicol., 5, 54 (1992), Tracy, T., et al.: Biochem. Pharmacol., 52, 1305 (1996), Bonnabry, P., et al.: Eur. J. Clin. Pharmacol., 49, 305 (1996), Rao, S., et al.: J. Med. Chem., 43, 2789 (2000), Hutzler, J., et al.: Drug Metab. Dispos., 29, 1029 (2001),

Formula: C₁₃H₁₂O₃

Color and Shape: Neat

Molecular weight: 216.23

Ref: TR-D292124

(R)-O-Desmethyl Naproxen

CAS: 123050-98-6

Formula: C₁₃H₁₂O₃

Molecular weight: 216.24

Ref: ST-EA-CP-N2043