CAS 123060-44-6

HOE 065

Description:

HOE 065, with the CAS number 123060-44-6, is a chemical compound that has been studied primarily for its pharmacological properties. It is known to act as a selective antagonist of certain receptors, which may contribute to its potential therapeutic applications. The compound typically exhibits moderate solubility in organic solvents and may have limited solubility in water, which is a common characteristic of many organic compounds. Its molecular structure includes functional groups that are crucial for its biological activity, influencing how it interacts with various biological targets. Additionally, HOE 065 may undergo metabolic transformations in biological systems, affecting its efficacy and safety profile. As with many chemical substances, handling and storage require adherence to safety protocols to mitigate any potential hazards. Overall, HOE 065 represents a compound of interest in medicinal chemistry, particularly in the context of drug development and receptor biology.

Formula: C₃₅H₅₂N₂O₉

InChI: InChI=1/C31H48N2O5.C4H4O4/c1-4-6-7-8-9-13-21-38-31(36)28-22-25-17-14-18-27(25)33(28)29(34)23(3)32-26(30(35)37-5-2)20-19-24-15-11-10-12-16-24;5-3(6)1-2-4(7)8/h10-12,15-16,23,25-28,32H,4-9,13-14,17-22H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t23-,25-,26-,27-,28-;/m0./s1

Synonyms:

• Hoe 065
• Cyclopenta(c)pyrrole-1-carboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-, octyl ester, (1S-(1-alpha,2-(R*(R*)),3a-beta,6a-alpha))-, (Z)-2-butenedioate (1:1)
• octyl (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylate (2E)-but-2-enedioate (non-preferred name)

N-[2-(4'-Methylphenylacetonitrile)]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside

CAS: 123060-44-6

Ramipril is a drug used for the treatment of high blood pressure and congestive heart failure. It belongs to the group of ACE inhibitors, which inhibit the enzyme angiotensin-converting enzyme (ACE). Ramipril is not active in its prodrug form, but is converted in vivo to enalaprilat, its active metabolite. This conversion takes place mainly in the liver. Enalaprilat prevents the conversion of angiotensin I to angiotensin II, reducing vasoconstriction. Ramipril also improves mental function by enhancing memory and cognition and may have an effect on improving learning ability. The effective dose for ramipril is 5-20 mg/kg per day, with captopril being an alternative medication that has similar effects.

Formula: C₃₅H₅₂N₂O₉

Purity: Min. 95%

Molecular weight: 644.8 g/mol

Ref: 3D-MM08499