CAS 1231-93-2

etynodiol

Description:

Etynodiol, also known as etynodiol diacetate, is a synthetic progestin used in hormonal contraceptives and hormone replacement therapy. It is characterized by its chemical structure, which includes a steroid backbone with specific functional groups that confer its biological activity. Etynodiol is typically administered in the form of its acetate derivative, which enhances its lipophilicity and bioavailability. The substance exhibits progestational activity, meaning it mimics the effects of the natural hormone progesterone, thereby influencing the menstrual cycle and supporting pregnancy. Etynodiol is known for its relatively low androgenic activity compared to other progestins, making it a preferred choice in formulations aimed at minimizing side effects related to androgen excess. Its pharmacokinetics involve absorption, metabolism, and excretion processes that are crucial for its therapeutic efficacy. Safety profiles indicate potential side effects, including hormonal imbalances and cardiovascular risks, necessitating careful consideration in clinical use. Overall, etynodiol plays a significant role in reproductive health management through its hormonal modulation properties.

Formula: C₂₀H₂₈O₂

InChI: InChI=1/C20H28O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,14-18,21-22H,4-11H2,2H3/t14-,15-,16+,17+,18-,19-,20-/m0/s1

InChI key: InChIKey=JYILPERKVHXLNF-QMNUTNMBSA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=C[C@@H](O)CC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• (3Beta,17Beta)-17-Ethynylestr-4-Ene-3,17-Diol
• (3S,8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
• (3β,17α)-19-Norpregn-4-en-20-yne-3,17-diol
• 17-Alpha-Ethynyloestr-4-Ene-3-Beta,17-Beta-Diol
• 17α-Ethynyl-4-estrene-3β,17β-diol
• 17α-Ethynyl-4-oestrene-3β,17β-diol
• 19-Nor-17-Alpha-Pregn-4-En-20-Yne-3-Beta,17-Diol
• 19-Nor-17α-pregn-4-en-20-yne-3β,17-diol
• 19-Norpregn-4-en-20-yne-3,17-diol, (3β,17α)-
• 3β-Hydroxylynestrenol
• Ethinodiol
• Ethynodiol
• (17R)-19-Norpregn-4-en-20-yne-3β,17-diol

Ethynodiol

Controlled Product

CAS: 1231-93-2

Formula: C₂₀H₂₈O₂

Color and Shape: Neat

Molecular weight: 300.44

Ref: 04-C13356430

Ethynodiol

CAS: 1231-93-2

Formula: C₂₀H₂₈O₂

Molecular weight: 300.44

Ref: 4Z-E-083001

Ethynodiol

Controlled Product

CAS: 1231-93-2

Applications Ethynodiol is a steroidal progestin that inhibits luciferase expression.
References Daufeldt, S., et al.: J. Steroid Biochem., 85, 9 (2003); Schoonen, W. G. E. J., et al.: J. Steroid Biochem., 74, 213 (2000)

Formula: C₂₀H₂₈O₂

Color and Shape: Neat

Molecular weight: 300.44

Ref: TR-E932120

Ethynodiol-d6

Controlled Product

CAS: 1231-93-2

Applications Ethynodiol-d6 is the isotope labelled analog of Ethynodiol (E932120); a steroidal progestin that inhibits luciferase expression.
References Daufeldt, S., et al.: J. Steroid Biochem., 85, 9 (2003); Schoonen, W. G. E. J., et al.: J. Steroid Biochem., 74, 213 (2000)

Formula: C₂₀D₆H₂₂O₂

Color and Shape: Neat

Molecular weight: 306.472

Ref: TR-E932122

Ethynodiol-d6

Controlled Product

CAS: 1231-93-2

Ethynodiol diacetate is a synthetic estrogen that belongs to the estradiol benzoate group. It is used as a progestin in combination with an estrogen for hormonal contraception, and as an antifungal agent in the treatment of vaginal candidiasis. Ethynodiol diacetate has been shown to have a genotoxic activity, which may be due to its ability to inhibit DNA synthesis and repair. It also inhibits protein synthesis in bacteria by binding to 16S ribosomal RNA.

Formula: C₂₀H₂₈O₂

Purity: Min. 95%

Molecular weight: 300.4 g/mol

Ref: 3D-BAA23193