CAS 123107-74-4

2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine

CAS: 123107-74-4

2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a novel nucleotide analog that exhibits anticancer activity. It has been shown to inhibit the growth of human leukemia cells and enhance the cytotoxic effect of doxorubicin. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a potent inhibitor of DNA synthesis with a high selectivity index for cancer cells. This agent inhibits DNA synthesis by competing with deoxyribonucleosides for incorporation into the growing DNA strand. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is an activator at the adenine phosphoribosyltransferase (APRT) enzyme and may also have an effect on ribonucleotide reductase (R

Formula: C₂₆H₂₆N₆O₉

Purity: Min. 95%

Molecular weight: 566.5 g/mol

Ref: 3D-YEA10774