CAS 123154-38-1

(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol

Description:

The chemical substance known as (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol, with the CAS number 123154-38-1, is a chiral compound featuring a cyclohexanol core. This compound contains a dimethylamino group, which contributes to its basicity and potential for forming hydrogen bonds, enhancing its solubility in polar solvents. The presence of a methoxyphenyl group introduces aromatic characteristics, which can influence its electronic properties and interactions with biological systems. The specific stereochemistry indicated by the (1R,2R) configuration suggests that the compound may exhibit distinct pharmacological properties, as stereoisomers can have different biological activities. This compound may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its potential interactions with neurotransmitter systems. Additionally, its structural features may allow for various modifications, making it a candidate for further research in drug design and synthesis. Overall, the compound's unique structure and functional groups suggest a range of possible applications in both research and therapeutic contexts.

Formula: C₁₆H₂₅NO₂

InChI: InChI=1S/C16H25NO2/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3/t14-,16+/m1/s1

InChI key: InChIKey=TVYLLZQTGLZFBW-ZBFHGGJFSA-N

SMILES: O[C@]1([C@@H](CN(C)C)CCCC1)C2=CC(OC)=CC=C2

Synonyms:

• (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
• (+)-(R,R)-trans-Tramadol
• (+)-trans-Tramadol free base
• Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R-cis)-
• Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)-

(+)-Tramadol

Controlled Product

CAS: 123154-38-1

(+)-Tramadol is an opioid analgesic that binds to the μ-opioid receptor and inhibits the reuptake of serotonin and norepinephrine, which are neurotransmitters. The drug also has a painkilling effect by inhibiting the release of prostaglandins and leukotrienes. Tramadol has been shown to be effective in human diabetic neuropathy, as well as in animal models of inflammatory and neuropathic pain. Tramadol is metabolized extensively by the liver enzyme CYP2D6 and is excreted primarily through the kidneys. The drug has a half-life of about 6 hours in humans but can be increased to 12 hours in patients with renal impairment. Other side effects include cutaneous lesions, drug interactions, and air entrainment.

Formula: C₁₆H₂₅NO₂

Purity: Min. 95%

Molecular weight: 263.38 g/mol

Ref: 3D-FT28359

Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)-

CAS: 123154-38-1

Formula: C₁₆H₂₅NO₂

Color and Shape: Liquid

Molecular weight: 263.3752

Ref: IN-DA000K34