CAS 123155-06-6: Octakis(6-O-tert-butyldimethylsilyl)-γ-cyclodextrin

Description:Octakis(6-O-tert-butyldimethylsilyl)-γ-cyclodextrin is a modified form of γ-cyclodextrin, a cyclic oligosaccharide composed of eight glucose units. This compound features tert-butyldimethylsilyl groups attached to the hydroxyl groups at the 6-position of the glucose units, enhancing its hydrophobic properties and stability. The introduction of these silyl groups increases the lipophilicity of the molecule, making it useful for encapsulating hydrophobic compounds, which can improve their solubility and bioavailability. This modification also provides resistance to enzymatic degradation, making it suitable for various applications in pharmaceuticals, food science, and materials chemistry. The structural characteristics of octakis(6-O-tert-butyldimethylsilyl)-γ-cyclodextrin allow it to form inclusion complexes, which can be utilized in drug delivery systems and controlled release formulations. Additionally, its unique properties may facilitate the formation of nanocarriers and enhance the stability of sensitive compounds. Overall, this compound represents a versatile tool in the field of supramolecular chemistry and nanotechnology.

Formula:C₉₆H₁₉₂O₄₀Si₈

InChI:InChI=1S/C96H192O40Si8/c1-89(2,3)137(25,26)113-41-49-73-57(97)65(105)81(121-49)130-74-50(42-114-138(27,28)90(4,5)6)123-83(67(107)59(74)99)132-76-52(44-116-140(31,32)92(10,11)12)125-85(69(109)61(76)101)134-78-54(46-118-142(35,36)94(16,17)18)127-87(71(111)63(78)103)136-80-56(48-120-144(39,40)96(22,23)24)128-88(72(112)64(80)104)135-79-55(47-119-143(37,38)95(19,20)21)126-86(70(110)62(79)102)133-77-53(45-117-141(33,34)93(13,14)15)124-84(68(108)60(77)100)131-75-51(43-115-139(29,30)91(7,8)9)122-82(129-73)66(106)58(75)98/h49-88,97-112H,41-48H2,1-40H3/t49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-/m1/s1

InChI key:InChIKey=MKSDSPVSZRMRNY-YKBAZCJNSA-N

SMILES:OC1C(O)C2OC3OC(CO[Si](C)(C)C(C)(C)C)C(OC4OC(CO[Si](C)(C)C(C)(C)C)C(OC5OC(CO[Si](C)(C)C(C)(C)C)C(OC6OC(CO[Si](C)(C)C(C)(C)C)C(OC7OC(CO[Si](C)(C)C(C)(C)C)C(OC8OC(CO[Si](C)(C)C(C)(C)C)C(OC9OC(CO[Si](C)(C)C(C)(C)C)C(OC1OC2CO[Si](C)(C)C(C)(C)C)C(O)C9O)C(O)C8O)C(O)C7O)C(O)C6O)C(O)C5O)C(O)C4O)C(O)C3O

Synonyms:
Octa-(6-oxy-tert-butyl-dimethylsilyl)-γ-cyclodextrin
Octakis(6-O-tert-butyldimethylsilyl)-γ-cyclodextrin
2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-Hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontane, γ-cyclodextrin deriv.
γ-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G,6H-octakis-O-[(1,1-dimethylethyl)dimethylsilyl]-
6A,6B,6C,6D,6E,6F,6G,6H-Octakis-O-[(1,1-dimethylethyl)dimethylsilyl]-γ-cyclodextrin