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CAS 123172-94-1

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Heptakis-(2,3-di-O-acetyl-6-O-tert.-Butyldimethylsilyl)-beta-Cyclodextrin

Description:
Heptakis-(2,3-di-O-acetyl-6-O-tert.-butyldimethylsilyl)-beta-cyclodextrin is a modified form of beta-cyclodextrin, a cyclic oligosaccharide composed of seven glucose units. This compound features multiple functional groups that enhance its solubility and stability, making it useful in various applications, particularly in drug delivery and formulation. The acetyl groups provide increased lipophilicity, while the tert-butyldimethylsilyl group enhances the compound's resistance to hydrolysis and improves its compatibility with organic solvents. These modifications allow for better encapsulation of hydrophobic molecules, facilitating the formation of inclusion complexes. The compound exhibits properties such as improved bioavailability of drugs, controlled release profiles, and enhanced stability of sensitive compounds. Its unique structure allows it to form host-guest complexes, which are essential in pharmaceutical applications. Additionally, the presence of silyl and acetyl groups can influence the compound's interaction with biological systems, making it a subject of interest in medicinal chemistry and materials science. Overall, this modified beta-cyclodextrin serves as a versatile tool in enhancing the delivery and efficacy of various therapeutic agents.
Formula:C112H196O49Si7
InChI:InChI=1/C112H196O49Si7/c1-57(113)134-85-78-71(50-127-162(36,37)106(15,16)17)148-99(92(85)141-64(8)120)156-79-72(51-128-163(38,39)107(18,19)20)150-101(94(143-66(10)122)86(79)135-58(2)114)158-81-74(53-130-165(42,43)109(24,25)26)152-103(96(145-68(12)124)88(81)137-60(4)116)160-83-76(55-132-167(46,47)111(30,31)32)154-105(98(147-70(14)126)90(83)139-62(6)118)161-84-77(56-133-168(48,49)112(33,34)35)153-104(97(146-69(13)125)91(84)140-63(7)119)159-82-75(54-131-166(44,45)110(27,28)29)151-102(95(144-67(11)123)89(82)138-61(5)117)157-80-73(52-129-164(40,41)108(21,22)23)149-100(155-78)93(142-65(9)121)87(80)136-59(3)115/h71-105H,50-56H2,1-49H3/t71?,72?,73?,74?,75?,76?,77?,78-,79-,80-,81-,82-,83-,84-,85+,86+,87+,88+,89+,90+,91+,92+,93+,94+,95+,96+,97+,98+,99-,100-,101-,102-,103-,104-,105+/m1/s1
Synonyms:
  • Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin Tetradecaacetate
  • 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-[(1,1-diMethylethyl)diMethylsilyl]-β-cyclodextrin 2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-Tetradecaacetate
  • Heptakis(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)cyclomaltoheptaose
  • Heptakis-(2,3-di-O-acetyl-6-O-tert.-Butyldimethylsilyl)-beta-Cyclodextrin
  • Hydrodex β-TBDAc
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Found 2 products.
  • Heptakis(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)cyclomaltoheptaose
    Biosynth
    + Info

    Heptakis(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)cyclomaltoheptaose

    CAS:
    <p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>
    Formula:C112H196O49Si7
    Purity:Min. 95%
    Molecular weight:2,523.32 g/mol

    Ref: 3D-OH46499

    1g
    996.00€
    2g
    1,259.00€
    100mg
    303.00€
    250mg
    396.00€
    500mg
    633.00€
  • Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin Tetradecaacetate
    TRC
    + Info

    Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin Tetradecaacetate

    Controlled Product
    CAS:
    <p>Applications Compound used as stationary phase in HPLC columns to separate E and Z isomers<br>References Kasai, H., et al.: Chem. Pharm. Bull., 52, 311 (2004),<br></p>
    Formula:C112H196O49Si7
    Color and Shape:Neat
    Molecular weight:2523.32

    Ref: TR-H281090

    5g
    2,070.00€
    250mg
    251.00€
    2500mg
    1,523.00€