Product correctly added to cart.

Abemaciclib

CAS 1231929-97-7: Abemaciclib

Description:Abemaciclib is a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), primarily used in the treatment of certain types of breast cancer, particularly hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer. It functions by disrupting the cell cycle, thereby inhibiting cancer cell proliferation. Abemaciclib is administered orally and is characterized by its ability to penetrate tissues effectively, which contributes to its therapeutic efficacy. The substance has a molecular formula that reflects its complex structure, including multiple functional groups that enhance its binding affinity to the target kinases. Its pharmacokinetic profile indicates a moderate half-life, allowing for flexible dosing schedules. Common side effects associated with abemaciclib include diarrhea, fatigue, and neutropenia, necessitating regular monitoring of blood counts during treatment. Overall, abemaciclib represents a significant advancement in targeted cancer therapies, providing an option for patients with specific breast cancer subtypes.

Formula:C27H32F2N8

InChI:InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)

InChI key:InChIKey=UZWDCWONPYILKI-UHFFFAOYSA-N

SMILES:FC=1C=NC(=NC1C=2C=C(F)C=3N=C(N(C3C2)C(C)C)C)NC4=NC=C(C=C4)CN5CCN(CC)CC5

  • Synonyms:
  • 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-
  • Abemaciclib
  • Ly 2835210
  • Ly 2835219
  • N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine
  • N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine
  • Verzenio
  • Verzenios
  • LY2835219
Sort by


See more categories

This search does not contain any category.

Found 5 products.

discount label

Ref: IN-DA000K5A

1g124.00 €
5g270.00 €
10g469.00 €
100mg55.00 €
250mg63.00 €
Estimated delivery in United States, on Tuesday 4 Mar 2025
discount label

Abemaciclib

Controlled Product
CAS:1231929-97-7

Ref: 86-MM3932.00-0250

250mg1,427.00 €
Estimated delivery in United States, on Friday 7 Mar 2025
discount label

Abemaciclib

CAS:1231929-97-7

Ref: TM-T2381

5mg52.00 €
10mg65.00 €
25mg86.00 €
50mg96.00 €
100mg120.00 €
200mg154.00 €
500mg274.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
discount label

Abemaciclib

Controlled Product
CAS:1231929-97-7

Ref: TR-A115153

10mg130.00 €
50mg192.00 €
100mg360.00 €
Estimated delivery in United States, on Friday 14 Mar 2025
discount label

Abemaciclib

CAS:1231929-97-7

Ref: 3D-FE103812

1g732.00 €
5g1,252.00 €
10g1,878.00 €
250mg334.00 €
500mg461.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
Welcome to CymitQuimica!We use cookies to enhance your visit. We do not include advertising.

Please see our Cookies Policy for more details or adjust your preferences in "Settings".